59104-19-7 Usage
General Description
2-(4-Chloro-phenoxy)-acetamidine hydrochloride is a chemical compound with the molecular formula C8H10ClN3O.HCl. It is a derivative of acetamidine and is used as a selective and reversible inhibitor of the Na+/H+ exchanger isoform 1 (NHE1). The compound has been studied for its potential use in the treatment of various diseases, including cancer, cardiovascular disorders, and inflammatory conditions. It has also been investigated for its potential role in enhancing the efficacy of chemotherapy drugs. As a hydrochloride salt, it is typically used in laboratory research settings and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 59104-19-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,1,0 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 59104-19:
(7*5)+(6*9)+(5*1)+(4*0)+(3*4)+(2*1)+(1*9)=117
117 % 10 = 7
So 59104-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClN2O.ClH/c9-6-1-3-7(4-2-6)12-5-8(10)11;/h1-4H,5H2,(H3,10,11);1H
59104-19-7Relevant articles and documents
EFFECT OF REMOTE HETEROATOM SUBSTITUENTS ON STEREOCHEMISTRY IN 1,2 H MIGRATION TO DIVALENT CARBON. EVIDENCE FOR " NEGATIVE " HYPERCONJUGATION OF CARBENE LONE PAIR
Tomioka, Hideo,Hayashi, Norihiro,Inoue, Noboru,Izawa, Yasuji
, p. 1651 - 1654 (2007/10/02)
Aryloxymethylchlorocarbene generated by photolysis of the corresponding diazirine afforded α-aryloxy-β-chloroalkene.The thermodynamically less stable Z-products are the major isomers and its content becomes dominant as more electron-withdrawing groups are
