59115-71-8Relevant articles and documents
KOtBu mediated synthesis of phenanthridinones and dibenzoazepinones
Bhakuni, Bhagat Singh,Kumar, Amit,Balkrishna, Shah Jaimin,Sheikh, Javeed Ahmed,Konar, Sanjit,Kumar, Sangit
supporting information; experimental part, p. 2838 - 2841 (2012/07/28)
Synthesis of substituted phenanthridinones and dibenzoazepinones has been realized from 2-halo-benzamides in the presence of potassium tert-butoxide and a catalytic amount of 1,10-phenanthroline or AIBN. This new carbon-carbon bond forming reaction gives direct access to various biaryl lactams containing six- and seven-membered rings chemoselectively. Carbon-carbon coupling seems to proceed by the generation of a radical in the amide ring which leads to C-H arylation of aniline.
