59168-90-0Relevant articles and documents
Stereospecific Synthesis of Optically Active Phenylpropylene Oxides
Capriati, Vito,Florio, Saverio,Luisi, Renzo,Nuzzo, Irene
, p. 3330 - 3335 (2004)
The stereospecific lithiation of diastereomeric phenylpropylene oxides has been studied as well as the trapping reaction with electrophiles. The reduction of the cis-α-benzoylpropylene oxide to give prevalently the anti-epoxy alcohol has been investigated
A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides
Beller, Matthias,Junge, Kathrin,Leischner, Thomas,Li, Wu,Liu, Weiping
supporting information, p. 11321 - 11324 (2020/05/16)
A straightforward methodology for the synthesis of anti-Markovnikov-type alcohols is presented. By using a specific cobalt triphos complex in the presence of Zn(OTf)2 as an additive, the hydrogenation of epoxides proceeds with high yields and selectivities. The described protocol shows a broad substrate scope, including multi-substituted internal and terminal epoxides, as well as a good functional-group tolerance. Various natural-product derivatives, including steroids, terpenoids, and sesquiterpenoids, gave access to the corresponding alcohols in moderate-to-excellent yields.
Asymmetric epoxidation of conjugated olefins with dioxygen
Koya, Shota,Nishioka, Yota,Mizoguchi, Hirotaka,Uchida, Tatsuya,Katsuki, Tsutomu
supporting information; experimental part, p. 8243 - 8246 (2012/09/08)
A complex situation: Asymmetric epoxidation of conjugated olefins was achieved at room temperature using ruthenium complex 1 as the catalyst and air as the oxidant to give epoxides in up to 95 % ee (see scheme). When the product was acid sensitive, the reaction was carried out at 0 °C under oxygen. Copyright
