59352-87-3

Basic information

• Product Name: 2,3,7-triphenylpyrido[2,3-b]pyrazine
• Synonyms: 2,3,7-triphenylpyrido[2,3-b]pyrazine
• CAS NO: 59352-87-3
• Molecular Weight: 359.43
• Mol File: 59352-87-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,7-triphenylpyrido[2,3-b]pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,7-triphenylpyrido[2,3-b]pyrazine(59352-87-3)
• EPA Substance Registry System: 2,3,7-triphenylpyrido[2,3-b]pyrazine(59352-87-3)

Safety Data

• Hazardous Substances Data: 59352-87-3(Hazardous Substances Data)

Upstream product

• 38870-31-4 7-bromo-2,3-diphenyl-5-azaquinoxaline 
• 98-80-6 phenylboronic acid 
• 134-81-6 benzil 
• 38875-53-5 5-bromo-pyridine-2,3-diamine 

Relevant articles and documents

Synthesis of quinoxalines and pyrido[2,3-b]pyrazines by SuzukiMiyaura cross-coupling reaction

Abstract: Bromo-substituted quinoxalines and pyrido[2,3-b]pyrazines were synthesized by condensation reactions of aromatic 1,2-diamino and 1,2-diketone compounds. These compounds were used as common intermediates for postcondensation modification by SuzukiMiyaura coupling reaction to form aryl-substituted quinoxalines and pyrido[2,3-b]pyrazines. High-efficiency with improved product yield of aryl-substituted quinoxalines and pyrido[2,3-b]pyrazine derivatives was achieved by conducting a coupling reaction in presence of Pd(dppf)Cl2·CH2Cl2 in tetrahydrofuran (THF) using K2CO3 as base at reflux temperature. Graphical abstract: [Figure not available: see fulltext.].

Palladium-catalyzed cross-coupling reactions of 7-bromo-2,3-diphenyl- pyrido[2,3-b]pyrazine

First examples of palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, Heck and Buchwald-Hartwig reactions, are reported in the pyrido[2,3-b]pyrazine series. This methodology circumvents problems found in uncatalyzed nucleophilic sub