59434-20-7

Basic information

• Product Name: Benzene, 1,3,5-tris(phenylmethoxy)-
• Synonyms: Phloroglucinol tribenzyl ether;1,3,5-tris(benzyloxy)benzene;1,3,5-tri(O-benzyloxy)phloroglucinol;Benzene,1,3,5-tris(phenylmethoxy);1,3,5-tribenzylphloroglycinol;1,3,5-tribenzyloxybenzene;1,3,5-tri-O-benzylphloroglucinol;tri-O-benzylphloroglucinol
• CAS NO: 59434-20-7
• Molecular Formula: C27H24O3
• Molecular Weight: 396.486
• Mol File: 59434-20-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3,5-tris(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3,5-tris(phenylmethoxy)-(59434-20-7)
• EPA Substance Registry System: Benzene, 1,3,5-tris(phenylmethoxy)-(59434-20-7)

Safety Data

• Hazardous Substances Data: 59434-20-7(Hazardous Substances Data)

Usage

Description

Benzene, 1,3,5-tris(phenylmethoxy)-, also known as Phloroglucin Tribenzyl Ether, is an organic compound that serves as an intermediate in the synthesis of other compounds. It is characterized by its benzene ring with three phenylmethoxy groups attached at the 1, 3, and 5 positions.

Uses

Used in Pharmaceutical Industry:
Benzene, 1,3,5-tris(phenylmethoxy)is used as an intermediate in the synthesis of Phloroglucinol Glucuronide Sodium Salt (P340015), a compound that has been utilized in preliminary clinical studies for the treatment of Hodgkin's disease and melanoma. Its role in the synthesis process is crucial for the development of potential therapeutic agents against these types of cancer.

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 59291-87-1 1-benzyloxy-3,5-dihydroxybenzene 
• 100-51-6 benzyl alcohol 
• 2999-40-8 1,3,5-triacetoxybenzene 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 55018-94-5 2,4,6-tribenzyloxybenzoic acid 

Downstream Products

• 76799-32-1 N-(chlorosulfonyl)-2,4,6-tris(benzyloxy)benzamide 
• 72911-58-1 2,2',4,4',6-pentakisbenzyloxy-3'-chloro-6'-methylbenzophenone 
• 115130-39-7 1,3,5-tri-O-benzyl-2-C-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)benzene 
• 115130-70-6 2,4,6-tribenzyloxy-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)benzene 
• 332900-02-4 [⁽¹³⁾CO]-1-[2,4,6-tris(benzyloxy)phenyl]ethanone 
• 886204-61-1 1,3,5-Tris-benzyloxy-2-bromo-benzene 
• 1122102-03-7 (2Z)-2-benzylidene-4,6-di(benzyloxy)-1-benzofuran-3(2H)-one 
• 401470-15-3 3-(1,3-benzodioxol-5-yl)-3-chloro-1-[2,4-di(benzyloxy)-6-hydroxyphenyl]prop-2-en-1-one 
• 1122102-07-1 1-[2,4-di(benzyloxy)-6-hydroxyphenyl]-3-(3,4-dimethoxyphenyl)prop-2-yn-1-one 
• 401504-46-9 (E)-1,3-di(2,4,6-trimethoxyphenyl)-2-propen-1-one 
• 314-98-7 2,2,2-trifluoro-1-(2,4,6-trimethoxyphenyl)ethan-1-one 
• 1122102-01-5 2,2,2-trifluoro-1-[2,4,6-tri(benzyloxy)phenyl]ethan-2-one 
• 1220779-28-1 C₅₉H₆₀O₉ 
• 1220779-29-2 C₅₈H₅₈O₉ 

Relevant articles and documents

COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF AS INHIBITORS OF RAN GTPASE

Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions involving Ran GTPase.

Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans

A series of symmetric polyoxygenated dibenzofurans with 2-methylbutyril moieties at C-4 and C-6 were obtained from commercial phloroglucinol through a sequence of reactions that include monoacylation, iodination, Suzuki-Miyaura coupling, oxidative dimeriz

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