59436-09-8

Basic information

• Product Name: 1-BROMO-4-(2-METHOXY-VINYL)-BENZENE
• Synonyms: 1-BROMO-4-(2-METHOXY-VINYL)-BENZENE;Benzene, 1-broMo-4-(2-Methoxyethenyl)-
• CAS NO: 59436-09-8
• Molecular Formula: C₉H₉BrO
• Molecular Weight: 213.07
• Mol File: 59436-09-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BROMO-4-(2-METHOXY-VINYL)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-4-(2-METHOXY-VINYL)-BENZENE(59436-09-8)
• EPA Substance Registry System: 1-BROMO-4-(2-METHOXY-VINYL)-BENZENE(59436-09-8)

Safety Data

• Hazardous Substances Data: 59436-09-8(Hazardous Substances Data)

Usage

General Description

1-Bromo-4-(2-methoxy-vinyl)-benzene, also known as p-bromoanisole, is a chemical compound with the molecular formula C8H9BrO. It is a colorless to pale yellow liquid with a distinctive sweet, floral odor. This chemical is commonly used as a flavoring agent in the production of processed foods and beverages, as well as a fragrance in personal care products. It is also used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-Bromo-4-(2-methoxy-vinyl)-benzene is considered to be a potential environmental and human health hazard, and caution should be exercised when handling and using this compound.

InChI:InChI=1S/C9H9BrO/c1-11-7-6-8-2-4-9(10)5-3-8/h2-7H,1H3

Upstream product

• 67-56-1 methanol 
• 16116-78-2 (4-bromophenyl)(trimethylsilyl)acetylene 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 1122-91-4 4-bromo-benzaldehyde 
• 20763-19-3 (methoxymethylene)triphenylphosphorane 

Downstream Products

• 16532-79-9 4-Bromophenylacetonitrile 
• 27200-79-9 p-bromophenylacetaldehyde 
• 22421-88-1 4-bromobenzyl phenyl ketone 

Relevant articles and documents

Palladium-catalyzed synthesis of α-aryl acetophenones from styryl ethers and aryl diazonium saltsviaregioselective Heck arylation at room temperature

Preparation of α-aryl acetophenones from styryl ethers and aryldiazonium salts is described. The reaction is catalyzed by palladium acetate at room temperature in the absence of ligand and base. The developed method is highly attractive in terms of reaction conditions, substrate scope, functional group tolerance and yields. Synthetic applications of the present method are demonstrated by preparing α-aryl indoles and 3-aryl isocoumarin from styryl ethers.

I2-catalyzed regioselective oxo- and hydroxy-acyloxylation of alkenes and enol ethers: A facile access to α-acyloxyketones, esters, and diol derivatives

I2-catalyzed oxo-acyloxylation of alkenes and enol ethers with carboxylic acids providing for the high yield synthesis of α-acyloxyketones and esters is described. This unprecedented regioselective oxidative process employs TBHP and Et3/s