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59464-18-5

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59464-18-5 Usage

Description

(1S)-1,4-anhydro-1-(4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol is a complex chemical compound derived from ribitol, a sugar alcohol. It features a heterocyclic ring and a D-ribitol molecule linked to a tetrahydropyrimidin-5-yl group, which includes both thioxo and oxo functional groups. This unique structure endows the compound with distinctive chemical properties, making it a candidate for various applications, particularly in the pharmaceutical industry and organic synthesis.

Uses

Used in Pharmaceutical Industry:
(1S)-1,4-anhydro-1-(4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol is used as a potential pharmaceutical agent due to its unique molecular structure and possible biological activity. It may contribute to drug discovery and development efforts, offering new avenues for the treatment of various diseases and conditions.
Used in Organic Synthesis:
In the field of organic chemistry, (1S)-1,4-anhydro-1-(4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol serves as a valuable intermediate or building block in the synthesis of more complex organic compounds. Its distinctive functional groups and heterocyclic ring make it a versatile component in creating novel molecules with specific properties.
Used as a Research Tool:
(1S)-1,4-anhydro-1-(4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol is also utilized as a research tool in organic and medicinal chemistry. It aids scientists in understanding the relationship between molecular structure and biological activity, facilitating the advancement of knowledge in these scientific disciplines.

Check Digit Verification of cas no

The CAS Registry Mumber 59464-18-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,4,6 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59464-18:
(7*5)+(6*9)+(5*4)+(4*6)+(3*4)+(2*1)+(1*8)=155
155 % 10 = 5
So 59464-18-5 is a valid CAS Registry Number.

59464-18-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-thio-pseudo-U

1.2 Other means of identification

Product number -
Other names 2-thio-pseudouridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59464-18-5 SDS

59464-18-5Downstream Products

59464-18-5Relevant articles and documents

Alternative nucleic acid molecules and uses thereof

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Paragraph 2061; 2063, (2015/11/09)

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.

ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF

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Page/Page column 592, (2016/06/28)

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.

A stereocontrolled total synthesis of C-nucleosides

Sato,Hayakawa,Noyori

, p. 2515 - 2525 (2007/10/02)

A stereocontrolled, general synthesis of chiral C-nucleosides has been achieved through a common lactonic C- beta -glycoside intermediate which is readily obtainable from non-carbohydrate materials. The optically pure lactone having the natural D configuration is obtained through optical resolution of the seco acid by the Pirkle's method followed by relactonization. alpha -Aminomethylenation of the lactone with t-C//4H//9OCH left bracket N(CH//3 )//2 right bracket //2 yields 2-(2,3-0-isopropylidene- beta -D-ribofuranosyl)-2-(dimethylaminomethylene)acetic acid lactone, which undergoes base-assisted condensation with urea followed by deprotection to furnish naturally occurring pseudouridine. Analogously, construction of heterocycles using thiourea and guanidine converts the aminomethylene lactone to unnatural pyrimidine C-nucelosides, 2-thiopseudouridine and pseudoisocytidine, respectively.

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