59476-61-8 Usage
Description
(Isoxazolin-5-on-2-yl)alanine, also known as a non-proteinogenic L-alpha-amino acid, is a derivative of L-alanine where one of the methyl hydrogens is substituted by a 5-oxoisoxazolin-2-yl group. This unique structure grants it potential applications in various fields due to its distinct chemical properties.
Uses
Used in Pharmaceutical Industry:
(Isoxazolin-5-on-2-yl)alanine is used as a building block for the synthesis of novel pharmaceutical compounds. Its unique structure allows for the development of new drugs with specific targeting and therapeutic properties, potentially leading to more effective treatments for various diseases.
Used in Chemical Research:
In the field of chemical research, (isoxazolin-5-on-2-yl)alanine serves as a valuable compound for studying the effects of structural modifications on the properties and reactivity of amino acids. This can contribute to a deeper understanding of the role of amino acids in biological systems and the development of new bioactive molecules.
Used in Material Science:
(Isoxazolin-5-on-2-yl)alanine can be utilized as a component in the development of new materials with specific properties, such as improved stability or enhanced biocompatibility. Its incorporation into polymers or other materials may lead to innovative applications in various industries, including medical, environmental, and industrial sectors.
Used in Agricultural Industry:
(Isoxazolin-5-on-2-yl)alanine may also find applications in the agricultural industry, potentially serving as a component in the development of new pesticides, herbicides, or fertilizers. Its unique structure could contribute to the creation of more effective and environmentally friendly products for crop protection and enhancement.
Check Digit Verification of cas no
The CAS Registry Mumber 59476-61-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,4,7 and 6 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 59476-61:
(7*5)+(6*9)+(5*4)+(4*7)+(3*6)+(2*6)+(1*1)=168
168 % 10 = 8
So 59476-61-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O4/c7-4(6(10)11)3-8-2-1-5(9)12-8/h1-2,4H,3,7H2,(H,10,11)/t4-/m0/s1
59476-61-8Relevant articles and documents
Biosynthesis of β-(isoxazolin-5-on-2-yl)alanine, the precursor of the neurotoxic amino acid β-N-oxalyl-L-α,β-diaminopropionic acid
Ikegami,Itagaki,Ishikawa,Ongena,Kuo,Lambein,Murakoshi
, p. 3376 - 3377 (1991)
β-(Isoxazolin-5-on-2-yl)alanine (BIA), a biosynthetic precursor of the neurotoxic amino acid β-N-oxalyl-L-α,β-diaminopropionic acid (ODAP), was confirmed to be derived from O-acetyl-L-serine (OAS) and isoxazolin-5-one by cysteine synthase in higher plants. Some properties of this enzyme in the biosynthesis of BIA are described.
Synthesis of chiral isoxazolidin-5-ones and their applications to the synthesis of β-amino-alanines and β-(N-hydroxyamino)-alanines
Baldwin, Jack E.,Adlington, Robert M.,Mellor, Lisa C.
, p. 5049 - 5066 (2007/10/02)
Herein we report a high-yielding synthesis of isoxazolidin-5-ones and their use to synthesise both β-amino-alanines and β-(N-hydroxyamino)-alanines.
SYNTHESIS OF L-β-(ISOXAZOLIN-5-ONE-2-YL)-ALANINE: A NOVEL METHOD FOR THE SYNTHESIS OF N-SUBSTITUTED 3,4-UNSUBSTITUTED ISOXAZOLIN-5-ONES
Baldwin, Jack E.,Adlington, Robert M.,Birch, David J.
, p. 5931 - 5934 (2007/10/02)
A mild new general method for the synthesis of the isoxazolin-5-one-2-yl ring system (4) via a favoured 5-endo-dig cyclisation is described; this methodology has been successfully applied for the first chemical enantio-efficient synthesis of L-β-(isoxazol
