594847-60-6

Basic information

• Product Name: (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-[3-(toluene-4-sulfonyloxy)-propyl]-tetrahydro-pyran-2-carboxylic acid methyl ester
• Synonyms: (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-[3-(toluene-4-sulfonyloxy)-propyl]-tetrahydro-pyran-2-carboxylic acid methyl ester
• CAS NO: 594847-60-6
• Molecular Weight: 747.226
• Mol File: 594847-60-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-[3-(toluene-4-sulfonyloxy)-propyl]-tetrahydro-pyran-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-[3-(toluene-4-sulfonyloxy)-propyl]-tetrahydro-pyran-2-carboxylic acid methyl ester(594847-60-6)
• EPA Substance Registry System: (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-[3-(toluene-4-sulfonyloxy)-propyl]-tetrahydro-pyran-2-carboxylic acid methyl ester(594847-60-6)

Safety Data

• Hazardous Substances Data: 594847-60-6(Hazardous Substances Data)

Upstream product

• 594847-58-2 (2S,3R,4R,5S,6S)-6-Allyl-3,4,5-tris-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 594847-57-1 (2S,3R,4R,5S,6S)-6-Allyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 252000-95-6 methyl (3,4-di-O-tert-butyldimethylsilyl-2,3-anhydro)-D-glucuronate 
• 252000-90-1 methyl (3,4-di-O-tert-butyldimethylsilyl-D-glucuronate)glycal 
• 98-59-9 p-toluenesulfonyl chloride 
• 594847-59-3 (2S,3R,4R,5S,6S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-6-(3-hydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid methyl ester 

Downstream Products

• 594847-61-7 C₅₆H₉₁NO₈Si₃ 

Relevant articles and documents

An evaluation of a C-glucuronide as a liver targeting group: Conjugate of a glucocorticoid antagonist

A β-C-glucuronide conjugate of the glucocorticoid receptor antagonist, Mifepristone 1, was prepared which maintained binding affinity, had modest in vitro activity, and was metabolically more stable than the parent. Pharmacokinetic studies suggest that the conjugate is recognized by the liver like O-glucuronides and may undergo a portion of the enterohepatic recirculation loop.