59485-81-3Relevant articles and documents
COMPOSITIONS FOR TRANSFECTING mRNA INTO A CELL AND THEIR APPLICATIONS
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Page/Page column 60, (2020/05/29)
The present invention relates to compositions for transfecting a messenger RNA (m RNA) into a cell and their applications. The present invention is directed to a composition for transfecting a mRNA into a cell comprising a mRNA, at least one neutral lipid and a cationic lipid of formula (I), wherein R1 R2, R3, R4 and R5, (CH2)n and A- are as defined in the description. The present invention also relates to uses of said composition and to a method for in vitro transfection of live cells.
CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME
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Paragraph 0516; 0517; 0518; 0519, (2017/09/02)
An object of the present invention is to provide a crystal of a cyclic phosphonic acid sodium salt (2ccPA) with high purity and excellent storage stability and a method for producing the crystal. The present invention provides a crystal of a cyclic phosphonic acid sodium salt (2ccPA) represented by formula (1):
Process for limiting the penetration into the skin and/or the keratinous fibres of an active cosmetic and/or pharmaceutical agent
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, (2008/06/13)
A process, composition, and kit for limiting the penetration into the skin and/or the keratinous fibers of at least one cosmetically and/or pharmaceutically active agent present in a base cosmetic and/or pharmaceutical composition for topical application and in particular for reducing the rate of penetration into the skin and/or the keratinous fibers of the active agent(s). The process includes the joint use, with the base composition, of an effective amount of a dispersion of vesicles in a medium, the vesicles comprising at least one ceramide of formula (I): wherein R1 is chosen from saturated and unsaturated, linear and branched C1-C32 alkyl groups optionally substituted by at least one hydroxyl group, wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C35 acyls; and R2 is chosen from saturated and unsaturated, linear and branched C1-C50 alkyl groups optionally substituted by at least one hydroxyl groups, and wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C30 acyls.