595608-45-0Relevant articles and documents
Nucleophilic displacement reactions of 5′-derivatised nucleosides in a vibration ball mill
Eguaogie, Olga,Conlon, Patrick F.,Ravalico, Francesco,Sweet, Jamie S. T.,Elder, Thomas B.,Conway, Louis P.,Lennon, Marc E.,Hodgson, David R. W.,Vyle, Joseph S.
, p. 87 - 92 (2017)
Vibration ball-milling in a zirconia-lined vessel afforded clean and quantitative nucleophilic displacement reactions between 4-methoxybenzylthiolate salts and nucleoside 5′-halides or 5′-tosylates in five to 60 minutes. Under these conditions, commonly-e