5958-00-9

Basic information

• Product Name: NA
• CAS NO: 5958-00-9
• Molecular Weight: 185.225
• Mol File: 5958-00-9.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: NA(CAS DataBase Reference)
• NIST Chemistry Reference: NA(5958-00-9)
• EPA Substance Registry System: NA(5958-00-9)

Safety Data

• Hazardous Substances Data: 5958-00-9(Hazardous Substances Data)

Upstream product

• 15854-87-2 4-iodopyridine 
• 100-66-3 methoxybenzene 
• 578-57-4 2-bromoanisole 
• 93830-58-1 diethyl (pyridin-4-yl)borane 
• 110-86-1 pyridine 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 529-28-2 4-iodoanisol 
• 626-61-9 4-Chloropyridine 
• 81115-36-8 2,6-Di-furan-2-yl-4-(2-methoxy-phenyl)-pyridine 
• 55-22-1 pyridine-4-carboxylic acid 
• 5720-06-9 2-Methoxyphenylboronic acid 
• 19524-06-2 4-bromopyridine hydrochloride 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 86610-20-0 4-(2-hydroxyphenyl)pyridine 
• 82212-04-2 1,2,3,4,5,6-hexahydro-4-(2-methoxyphenyl)pyridine hydrochloride 
• 81115-40-4 4-(2-hydroxyphenyl)-1-methylpyridinium iodide 
• 87308-05-2 2-[2-(Pyridin-4-yl)phenoxy]acetonitrile 
• 83420-56-8 4-(2-ethynylphenyl)pyridine 
• 1004760-10-4 4-(2-methoxyphenyl)pyridine hydrochloride 
• 81115-34-6 1-methyl-4-(2-(2-ethoxy-2-oxoethoxy)phenyl)pyridinium iodide 
• 81115-41-5 4-<2-(2-oxopropoxy)phenyl>pyridine 
• 86610-23-3 spiro<(2-(1-oxoethyl)benzofuran)-3(2H),4'(1'H)-(1-(phenyloxomethyl)pyridine)> 
• 86610-21-1 ethyl-2(4-pyridinyl)phenoxyacetate 

Relevant articles and documents

Quantifying Through-Space Substituent Effects

The description of substituents as electron donating or withdrawing leads to a perceived dominance of through-bond influences. The situation is compounded by the challenge of separating through-bond and through-space contributions. Here, we probe the experimental significance of through-space substituent effects in molecular interactions and reaction kinetics. Conformational equilibrium constants were transposed onto the Hammett substituent constant scale revealing dominant through-space substituent effects that cannot be described in classic terms. For example, NO2 groups positioned over a biaryl bond exhibited similar influences as resonant electron donors. Meanwhile, the electro-enhancing influence of OMe/OH groups could be switched off or inverted by conformational twisting. 267 conformational equilibrium constants measured across eleven solvents were found to be better predictors of reaction kinetics than calculated electrostatic potentials, suggesting utility in other contexts and for benchmarking theoretical solvation models.

Metal-free arylation of benzene and pyridine promoted by amino-linked nitrogen heterocyclic carbenes

An amino-linked nitrogen heterocyclic carbene (amino-NHC), 1-tBu, has been shown to mediate carbon-carbon coupling through the direct C-H functionalization of benzene and pyridine in the absence of a metal catalyst. Using EPR, the first spectroscopic evidence corroborating the single electron transfer mechanism for the metal-free carbon-carbon coupling manifold, as reported by others, is introduced.

AZABENZIMIDAZOLYL COMPOUNDS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I), as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.