596107-17-4Relevant articles and documents
5-Endo-dig electrophilic cyclization of α-alkynyl carbonyl compounds: Synthesis of novel bicyclic 5-iodo- and 5-bromofuranopyrimidine nucleosides
Srinivasa Rao, Meneni,Esho, Noor,Sergeant, Craig,Dembinski, Roman
, p. 6788 - 6790 (2003)
5-Endo-dig electrophilic cyclization of 5-alkynyl-2′-deoxyuridines with N-iodosuccinimide or N-bromosuccinimide in acetone at room temperature gives 3-(2′-deoxy-β-D-ribofuranosyl)-5-halo-2,3-dihydrofuro[2,3-d] pyrimidin-2-ones that usually precipitate fro
5-Alkynyl-2′-deoxyuridines: Chromatography-free synthesis and cytotoxicity evaluation against human breast cancer cells
Meneni, Srinivasarao,Ott, Ingo,Sergeant, Craig D.,Sniady, Adam,Gust, Ronald,Dembinski, Roman
, p. 3082 - 3088 (2008/02/01)
Starting with 5-iodo-2′-deoxyuridine, a series of 5-alkynyl-2′-deoxyuridines (with n-propyl, cyclopropyl, 1-hydroxycyclohexyl, p-tolyl, p-tert-butylphenyl, p-pentylphenyl, and trimethylsilyl alkyne substituents) have been synthesized via the palladium-cat