5963-77-9 Usage
Description
2-Pentynoic Acid, also known as pent-4-ynoic acid, is an organic compound characterized by its unique structure that features a triple bond and a carboxylic acid group. This molecule is known for its reactivity and versatility in chemical synthesis, making it a valuable building block for creating a wide range of organic molecules.
Uses
Used in Chemical Synthesis:
2-Pentynoic Acid is used as a chemical reagent for the preparation of various organic molecules. Its triple bond and carboxylic acid group provide a foundation for further reactions and modifications, allowing for the creation of a diverse array of compounds.
Used in Stereoselective Synthesis of Vinylstannanes:
In the field of organic chemistry, 2-Pentynoic Acid is employed as a key component in the stereoselective synthesis of vinylstannanes. These organostannane compounds are important intermediates in various chemical reactions, particularly in the formation of carbon-carbon bonds. The use of 2-Pentynoic Acid in this process helps to control the stereochemistry of the resulting molecules, which is crucial for their biological activity and potential applications.
Used in Synthesis of Spiroindolines Derivatives:
2-Pentynoic Acid also plays a significant role in the synthesis of spiroindolines derivatives. Spiroindolines are a class of organic compounds with a unique spiro fused indoline structure, which exhibit a range of biological activities and potential applications in the pharmaceutical industry. The incorporation of 2-Pentynoic Acid in the synthesis process allows for the creation of novel spiroindoline derivatives with tailored properties and functionalities.
Check Digit Verification of cas no
The CAS Registry Mumber 5963-77-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,6 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5963-77:
(6*5)+(5*9)+(4*6)+(3*3)+(2*7)+(1*7)=129
129 % 10 = 9
So 5963-77-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H6O2/c1-2-3-4-5(6)7/h2H2,1H3,(H,6,7)
5963-77-9Relevant articles and documents
ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES
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Page/Page column 36, (2019/02/06)
Aspects of the present application relate to process for the preparation of Pyrrolidine derivatives useful as key intermediates for active ingredients. Specific aspects relate to alternate process for the preparation of Upadacitinib intermediate, 4-ethylpyrrolidine-3-carboxylic acid, its ester or a salt thereof. Processes disclosed here in are cost effective and industrially viable as compared to known processes.
Palladium-catalyzed oxidative aminocarbonylation by decarboxylative coupling: Synthesis of alkynyl amides
Hwang, Jinil,Choi, Jinseop,Park, Kyungho,Kim, Wonyoung,Song, Kwang Ho,Lee, Sunwoo
, p. 2235 - 2243 (2015/04/14)
Alkynyl amides were synthesized from a palladium-catalyzed coupling reaction of alkynyl carboxylic acids and amines under carbon monoxide. The reaction was conducted with palladium(II) acetate (5 mol-%) and silver(I) oxide (1.0 equiv.) in acetonitrile at 80 °C for 1 h. This method provides good to moderate product yields and good functional group tolerance towards ketone, ester, and nitrile groups.
