59669-16-8 Usage
Description
OCTANOIC 1-13C ACID, also known as Octanoic acid-13C, is a medium-chain saturated fatty acid that is labeled with the stable isotope carbon-13. It is commonly used as an internal standard for the quantification of octanoic acid by gas chromatography (GC) or liquid chromatography-mass spectrometry (LC-MS). OCTANOIC 1-13C ACID has been identified in Teleme cheeses made from goat, ovine, or bovine milk and exhibits activity against various bacteria, such as S. mutans, S. gordonii, F. nucleatum, and P. gingivalis. Additionally, OCTANOIC 1-13C ACID levels are increased in the plasma of patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, an inborn error of fatty acid metabolism characterized by hypoketotic hypoglycemia, medium-chain dicarboxylic aciduria, and intolerance to fasting. OCTANOIC 1-13C ACID is in a liquid state.
Uses
1. Used in Synthesis of 13C Labeled Cholesterin Carboxylates:
OCTANOIC 1-13C ACID is used as a precursor for the synthesis of 13C labeled cholesterol carboxylates, which are essential for various research applications and understanding the metabolic pathways of cholesterol.
2. Used in Analytical Chemistry as an Internal Standard:
OCTANOIC 1-13C ACID is used as an internal standard for the quantification of octanoic acid in various samples, such as food products and biological samples, by employing GC or LC-MS techniques. This application aids in enhancing the accuracy and precision of the analytical results.
3. Used in Research on MCAD Deficiency:
OCTANOIC 1-13C ACID is utilized in research studies to investigate the role of octanoic acid in patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. This helps in understanding the underlying mechanisms of the disease and developing potential therapeutic strategies.
4. Used in Antimicrobial Research:
OCTANOIC 1-13C ACID is employed in antimicrobial research to study its activity against various bacteria, such as S. mutans, S. gordonii, F. nucleatum, and P. gingivalis. This information can be valuable for developing new antimicrobial agents and understanding the mode of action of OCTANOIC 1-13C ACID against these bacteria.
5. Used in Food Industry:
In the food industry, OCTANOIC 1-13C ACID can be used as a reference compound for the analysis of octanoic acid content in various cheese products, such as Teleme cheeses made from goat, ovine, or bovine milk. This helps in ensuring the quality and safety of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 59669-16-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,6,6 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59669-16:
(7*5)+(6*9)+(5*6)+(4*6)+(3*9)+(2*1)+(1*6)=178
178 % 10 = 8
So 59669-16-8 is a valid CAS Registry Number.
59669-16-8Relevant articles and documents
Catalytic Decarboxylation/Carboxylation Platform for Accessing Isotopically Labeled Carboxylic Acids
Tortajada, Andreu,Duan, Yaya,Sahoo, Basudev,Cong, Fei,Toupalas, Georgios,Sallustrau, Antoine,Loreau, Olivier,Audisio, Davide,Martin, Ruben
, p. 5897 - 5901 (2019/06/17)
An integrated catalytic decarboxylation/carboxylation for accessing isotopically labeled carboxylic acids with13CO2 or14CO2 is described. The method shows a wide scope under mild conditions, even in the context of late-stage functionalization, and does not require stoichiometric organometallics, thus complementing existing carbon-labeling techniques en route to carboxylic acids.
