59670-27-8

Basic information

• Product Name: 4-methoxybenzaldehyde N-acetylhydrazone
• Synonyms: 4-methoxybenzaldehyde N-acetylhydrazone
• CAS NO: 59670-27-8
• Molecular Weight: 192.217
• Mol File: 59670-27-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-methoxybenzaldehyde N-acetylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxybenzaldehyde N-acetylhydrazone(59670-27-8)
• EPA Substance Registry System: 4-methoxybenzaldehyde N-acetylhydrazone(59670-27-8)

Safety Data

• Hazardous Substances Data: 59670-27-8(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 1068-57-1 acetic acid hydrazide 

Downstream Products

• 39659-76-2 3-(4-methoxy-phenyl)-1,5-diphenyl-pentane-1,5-dione 
• 1416358-47-8 C₁₈H₁₈N₂O 
• 1236179-30-8 1-(3-(4-fluorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 724745-11-3 1-(3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 1236179-32-0 1-(3,4-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 123716-68-7 1-(4-methyl-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 1236179-33-1 1-(4-phenyl-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 1236179-26-2 1-(3,4-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone 
• 25877-54-7 methyl 4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl ether 

Relevant articles and documents

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.

Unexpected synthesis of 1,3,5-triarly-1,5-diketones from aryl ketones via di-enamine mechanism

An unexpected reaction of aryl ketone with acetohydrazone of aromatic aldehyde via 1,2-di-enamine/di-iminium mechanism was discovered, leading to efficient synthesis of 1,3,5-triaryl-1,5-diketones in good to excellent yields.

β-Acetyl-β-nitrostyrenes: Structure and use for synthesis of heteryl-containing structures

1H, IR, and electronic absorption spectroscopy and X-ray diffraction analysis were used to establish that 1-acetyl-1-nitro-2-phenyl-and 2-(p-methoxyphenyl)ethenes have Z configuration, and their 2-(p-N, Ndimethylaminophenyl)-substituted analog exists in chloroform-d 3 as a mixture of Z and E isomers. The reactions of gem-acetylnitroethenes with N-methylpyrrole were shown to involve alkylation at the C2-reaction center of the heterocycle. The reactions of these nitroalkenes with hydrazine form pyrazoles and azines, with acetylhydrazine, the corresponding hydrazones (via transalkenylation), and with sodium azide, acetylsubstituted 1,2,3-triazoles.