59693-95-7

Basic information

• Product Name: 1-chloro-4-cyclohexylsulfanyl-benzene
• Synonyms: 1-chloro-4-cyclohexylsulfanyl-benzene
• CAS NO: 59693-95-7
• Molecular Formula: C₁₂H₁₅ClS
• Molecular Weight: 0
• Mol File: 59693-95-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 325.4°C at 760 mmHg
• Flash Point: 143.2°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 0.000437mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 1-chloro-4-cyclohexylsulfanyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-cyclohexylsulfanyl-benzene(59693-95-7)
• EPA Substance Registry System: 1-chloro-4-cyclohexylsulfanyl-benzene(59693-95-7)

Safety Data

• Hazardous Substances Data: 59693-95-7(Hazardous Substances Data)

Usage

Classification

Organochlorine compound

Structure

a. Benzene ring
b. Chlorine atom at the 1-position
c. Cyclohexylsulfanyl group at the 4-position

Applications

a. Organic synthesis
b. Synthetic intermediate in pharmaceuticals and agrochemicals production

Health hazards

a. Harmful if swallowed
b. Harmful if inhaled
c. Harmful if absorbed through the skin
d. Causes eye irritation
e. Causes respiratory tract irritation

Safety measures

Proper handling and safety measures are necessary when working with 1-chloro-4-cyclohexylsulfanyl-benzene.

InChI:InChI=1/C12H15ClS/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h6-9,11H,1-5H2

Upstream product

• 108-85-0 1-bromocyclohexane 
• 106-54-7 p-Chlorothiophenol 
• 98-89-5 Cyclohexanecarboxylic acid 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 126812-30-4 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate 
• 110-82-7 cyclohexane 
• 26760-21-4 methyl p-chlorobenzenesulphinate 
• 2751-25-9 p-chlorophenylsulfonyl hydrazide 
• 108-94-1 cyclohexanone 
• 74314-71-9 C₁₈H₁₈Cl₂S₂ 
• 110-83-8 cyclohexene 
• 613245-35-5 1-(p-chlorophenylsulfinyl)-1-(p-chlorophenylthio)cyclohexane 
• 1569-69-3 Cyclohexanethiol 
• 1679-18-1 4-Chlorophenylboronic acid 

Downstream Products

• 13343-26-5 phenyl p-chlorophenyl sulfide 

Relevant articles and documents

Visible-Light-Mediated Alkylation of Thiophenols via Electron Donor-Acceptor Complexes Formed between Two Reactants

A metal-free, photocatalyst-free, photochemical system was developed for the direct alkylation of thiophenols via electron donor-acceptor (EDA) complexes (KEDA = 145 M-1) between two reactants, N-hydroxyphthalimide esters as acceptors and thiophenol anions as donors, in the presence of a tertiary amine. The EDA complexes in the reaction system have a broad range of visible-light absorption (400-650 nm) and can trigger the reaction effectively under sunlight.

Deprotonated Salicylaldehyde as Visible Light Photocatalyst

Salicylaldehyde is established as an efficient visible light photocatalyst for the first time. Compared to other simple aldehyde analogies, salicylaldehyde has a unique deprotonative red-shift from 324 to 417 nm and gives rise to the remarkable increase of fluorescence quantum from 0.0368 to 0.4632, thus enabling salicylaldehyde as a visible light (>400 nm) photocatalyst. The experimental investigations suggest that the reactive radical species are generated by sensitization of the substrates by the deprotonated salicylaldehyde through an energy-transfer pathway. Consequently, the C-C cleaving alkylation reactions of N-hydroxyphthalimide esters proceed smoothly in the presence of as low as 1 mol % of salicylaldehyde under the visible-light irradiation, affording desired alkylation products with up to 99% yields. Application in visible-light induced aerobic oxidation of N-alkylpyridinium salts is also reported.

Palladium-catalyzed thiolation of alkanes and ethers with arylsulfonyl hydrazides

A new method for the preparation of alkyl aryl sulfides through direct oxidative thiolation of alkanes or ethers with arylsulfonyl hydrazides using di-tert-butyl peroxide (DTBP) as an oxidant catalyzed by Pd(OAc)2 has been reported. The C-H bonds in various alkanes or ethers were successfully converted into C-S bonds to yield the corresponding sulfides in moderate to good yields. the Partner Organisations 2014.