597-71-7Relevant articles and documents
A Mild, General, Metal-Free Method for Desulfurization of Thiols and Disulfides Induced by Visible-Light
Qiu, Wenting,Shi, Shuai,Li, Ruining,Lin, Xianfeng,Rao, Liangming,Sun, Zhankui
supporting information, p. 1255 - 1258 (2021/05/05)
A visible-light-induced metal-free desulfurization method for thiols and disulfides has been explored. This radical desulfurization features mild conditions, robustness, and excellent functionality compatibility. It was successfully applied not only to the desulfurization of small molecules, but also to peptides.
Synthesis of dipentaerythritol from pentaerythritol under acidic conditions
Landart, Mélissa,Lemaire, Marc,Métay, Estelle
supporting information, p. 2591 - 2603 (2020/12/29)
The direct synthesis of dipentaerythritol (DPE) from pentaerythritol (PE) was studied under acidic conditions. After optimization of the reaction parameters in a batch reactor, DPE was obtained with 50% selectivity when 50% PE was converted. This process, using PE in suspension in sulfolane (PE/sulfolane ratio = 2333 g/L) at 175 °C for 60 min, required a low amount of sulfuric acid (0.5 mol %). The optimized conditions were transposed to a 140 grams scale process. Finally, DPE was isolated with 16% yield (72% gas chromatography, GC purity) for 28% conversion of PE that corresponds to 57% DPE selectivity.
Folding control of a non-natural glycopeptide using saccharide-coded structural information for polypeptides
Fujii, Naoka,Haino, Takeharu,Ishido, Yuki,Kanbayashi, Naoya,Okamura, Taka-Aki,Onitsuka, Kiyotaka
supporting information, p. 2767 - 2770 (2020/03/13)
We synthesized "glyco-arylopeptides", whose folding structure significantly changes depending on the kind of saccharide in their side chain. The saccharide moiety interacts with the main chain via hydrogen bonding, and the non-natural polypeptides form two well-defined architectures - (P)-31- and (M)-41-helices - depending on the length of the saccharide chains and even the configuration of a single stereo-genic center in the epimers.