59734-16-6

Basic information

• Product Name: N-heptylformamide
• Synonyms: N-heptylformamide
• CAS NO: 59734-16-6
• Molecular Formula: C₈H₁₇NO
• Molecular Weight: 143.23
• Mol File: 59734-16-6.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 262°C at 760 mmHg
• Flash Point: 148.7°C
• Appearance: /
• Density: 0.859g/cm³
• Vapor Pressure: 0.0112mmHg at 25°C
• Refractive Index: 1.427
• CAS DataBase Reference: N-heptylformamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-heptylformamide(59734-16-6)
• EPA Substance Registry System: N-heptylformamide(59734-16-6)

Safety Data

• Hazardous Substances Data: 59734-16-6(Hazardous Substances Data)

Usage

Description

N-heptylformamide is a chemical compound with the formula C8H17NO. It is an organic compound characterized by a heptyl group (a straight chain seven-carbon alkyl group) attached to the nitrogen atom of the formamide functional group. This colorless liquid with a mild odor is known for its versatile properties, making it suitable for use across a wide range of industries.

Uses

Used in Pharmaceutical Industry:
N-heptylformamide is used as a solvent in the production of pharmaceuticals, facilitating various chemical processes that are essential for the synthesis of drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, N-heptylformamide serves as a solvent, aiding in the manufacturing process of agricultural chemicals that are vital for crop protection and enhancement of yield.
Used in Polymer Industry:
N-heptylformamide is utilized as a solvent in the production of polymers, contributing to the creation of a diverse array of polymeric materials used in numerous applications.
Used as a Corrosion Inhibitor:
N-heptylformamide is employed as a corrosion inhibitor, helping to protect materials and structures from the damaging effects of corrosion, thereby extending their service life and maintaining their integrity.
Used as an Intermediate in Organic Synthesis:
N-heptylformamide also serves as an intermediate in the synthesis of other organic compounds, playing a crucial role in the creation of a variety of chemical products.

InChI:InChI=1/C8H17NO/c1-2-3-4-5-6-7-9-8-10/h8H,2-7H2,1H3,(H,9,10)

Upstream product

• 111-68-2 1-Heptylamine 
• 96-26-4 dihydroxyacetone 
• 56-81-5 glycerol 
• 50-00-0 formaldehyd 
• 109-94-4 formic acid ethyl ester 
• 124-38-9 carbon dioxide 
• 111-64-8 n-octanoic acid chloride 
• 36551-86-7 octanoyl azide 
• 4747-81-3 N-heptylisocyanate 
• 153469-63-7 Heptyl-selenocarbamic acid Se-phenyl ester 
• 64-18-6 formic acid 

Downstream Products

• 67-56-1 methanol 
• 111-68-2 1-Heptylamine 

Relevant articles and documents

Highly Efficient and Selective N-Formylation of Amines with CO2 and H2 Catalyzed by Porous Organometallic Polymers

The valorization of carbon dioxide (CO2) to fine chemicals is one of the most promising approaches for CO2 capture and utilization. Herein we demonstrated a series of porous organometallic polymers could be employed as highly efficient and recyclable catalysts for this purpose. Synergetic effects of specific surface area, iridium content, and CO2 adsorption capability are crucial to achieve excellent selectivity and yields towards N-formylation of diverse amines with CO2 and H2 under mild reaction conditions even at 20 ppm catalyst loading. Density functional theory calculations revealed not only a redox-neutral catalytic pathway but also a new plausible mechanism with the incorporation of the key intermediate formic acid via a proton-relay process. Remarkably, a record turnover number (TON=1.58×106) was achieved in the synthesis of N,N-dimethylformamide (DMF), and the solid catalysts can be reused up to 12 runs, highlighting their practical potential in industry.

Amine formylation with CO2 and H2 catalyzed by heterogeneous Pd/PAL catalyst

For the first time, Pd supported on natural palygorskite was developed for amine formylation with CO2 and H2. Both secondary and primary amines with diverse structures could be converted into the desired formamides at 100 °C, and good to excellent yields were obtained.

METHOD FOR PREPARING FORMAMIDE COMPOUND

Disclosed is a method for preparing a formamide compound, the method uses carbon dioxide, hydrogen and an amine compound as raw materials and a transition metal complex as a catalyst, and the reaction is carried out in an organic solvent or in the absence of a solvent to form a formamide compound. The method of the present invention is an effective method of chemical utilization of carbon dioxide, which has the advantages of high reaction efficiency, a good selectivity, mild conditions, economic and environmental protection, being simple and convenient to operate and the like, and has a good popularization and application prospect.