597540-60-8

Basic information

• Product Name: (2aR,2bR,4aS,4bS)-1-(4-Methoxy-benzyl)-2-oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester
• Synonyms: (2aR,2bR,4aS,4bS)-1-(4-Methoxy-benzyl)-2-oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester
• CAS NO: 597540-60-8
• Molecular Weight: 301.342
• Mol File: 597540-60-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2aR,2bR,4aS,4bS)-1-(4-Methoxy-benzyl)-2-oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2aR,2bR,4aS,4bS)-1-(4-Methoxy-benzyl)-2-oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester(597540-60-8)
• EPA Substance Registry System: (2aR,2bR,4aS,4bS)-1-(4-Methoxy-benzyl)-2-oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester(597540-60-8)

Safety Data

• Hazardous Substances Data: 597540-60-8(Hazardous Substances Data)

Upstream product

• 597540-59-5 (2aR,4aS,6aR,6bS)-4-(4-Methoxy-benzyl)-3-oxo-3,4,5,6,6a,6b-hexahydro-2aH-1,2,4-triaza-cyclopenta[cd]pentalene-4a-carboxylic acid methyl ester 

Downstream Products

• 176199-49-8 (1S,2S,5R,6R)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 
• 176199-48-7 eglumetad 
• 597540-62-0 (2aR,2bR,4aS,4bS)-2-Oxo-hexahydro-1-aza-cyclopropa[cd]pentalene-4a-carboxylic acid methyl ester 

Relevant articles and documents

Stereocontrolled synthesis of a potent agonist of group II metabotropic glutamate receptors, (+)-LY354740, and its related derivatives

Efficient synthesis of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740: 1) and its structurally related analogs (-)-2 and (-)-3 has been accomplished starting with (1S,2R)-1-amino-2-hydroxycyclopentane- or cyclohexanecarboxylic acid (4 or 17 ) via an intramolecular cyclopropanation of α-diazo acetamide.