59825-50-2

Basic information

• Product Name: 2-(2-bromoethoxy)-1,3-dimethoxybenzene
• CAS NO: 59825-50-2
• Molecular Formula: C₁₀H₁₃BrO₃
• Molecular Weight: 261.1124
• Mol File: 59825-50-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 302.6°C at 760 mmHg
• Flash Point: 121.6°C
• Density: 1.366g/cm³
• Vapor Pressure: 0.00176mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: 2-(2-bromoethoxy)-1,3-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromoethoxy)-1,3-dimethoxybenzene(59825-50-2)
• EPA Substance Registry System: 2-(2-bromoethoxy)-1,3-dimethoxybenzene(59825-50-2)

Safety Data

• Hazardous Substances Data: 59825-50-2(Hazardous Substances Data)

Usage

General Description

2-(2-bromoethoxy)-1,3-dimethoxybenzene is an organic chemical compound with the molecular formula C10H13BrO3. It is a colorless to pale yellow liquid with a benzene ring structure and two methoxy groups and one bromoethoxy group attached to it. 2-(2-bromoethoxy)-1,3-dimethoxybenzene is commonly used in organic synthesis and pharmaceutical research due to its potential for forming various derivatives with different functional groups. It is also used as a building block in the production of other complex organic compounds and can be used in the development of new drug molecules. Additionally, 2-(2-bromoethoxy)-1,3-dimethoxybenzene has potential applications as a starting material for the synthesis of dyes, pigments, and other fine chemicals.

Upstream product

• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 106-93-4 ethylene dibromide 
• 6161-82-6 2-(2',6'-dimethoxyphenoxy)ethanol 

Downstream Products

• 87780-25-4 1,4-bis-[2-(2,6-dimethoxy-phenoxy)-ethyl]-piperazine 
• 87780-28-7 N-[2-(2,6-dimethoxy-phenoxy)-ethyl]-phthalimide 
• 135420-79-0 1-<(2,6-dimethoxy)phenoxy>-2-<<(2-methoxy)phenoxy>ethylthio>ethane 
• 135420-77-8 1-<(1,4-benzodioxan-2-yl)methylthio>-2-<(2,6-dimethoxy)phenoxy>ethane 
• 40515-98-8 2-(2,6-dimethoxyphenoxy)ethylamine 
• 91005-66-2 2-(2,6-Dimethoxy-phenoxy)-ethylhydrazin 
• 1446339-40-7 (S)-3-{1-[2-(2,6-dimethoxyphenoxy)ethyl]piperidin-2-yl}pyridine oxalate 
• 87780-29-8 di<2-(2,6-dimethoxyphenoxy)ethyl>amine oxalate 
• 91677-53-1 3-(<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl)-1,4-dioxane<1,2-b>naphtalene 
• 91677-55-3 2-(<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl)-1,4-dioxane<1,2-b>naphtalene 
• 91677-51-9 2-(<<2-(2,6-dimethoxyphenoxy)ethyl>amino>methyl)-1,4-dioxane<2,3-b>naphtalene 

Relevant articles and documents

Synthesis, antimicrobial evaluation, and in silico studies of quinoline—1H-1,2,3-triazole molecular hybrids

Abstract: Antimicrobial resistance has become a significant threat to global public health, thus precipitating an exigent need for new drugs with improved therapeutic efficacy. In this regard, molecular hybridization is deemed as a viable strategy to afford multi-target-based drug candidates. Herein, we report a library of quinoline—1H-1,2,3-triazole molecular hybrids synthesized via copper(I)-catalyzed azide-alkyne [3 + 2] dipolar cycloaddition reaction (CuAAC). Antimicrobial evaluation identified compound 16 as the most active hybrid in the library with a broad-spectrum antibacterial activity at an MIC80 value of 75.39?μM against methicillin-resistant S. aureus, E. coli, A. baumannii, and multidrug-resistant K. pneumoniae. The compound also showed interesting antifungal profile against C. albicans and C. neoformans at an MIC80 value of 37.69 and 2.36?μM, respectively, superior to fluconazole. In vitro toxicity profiling revealed non-hemolytic activity against human red blood cells (hRBC) but partial cytotoxicity to human embryonic kidney cells (HEK293). Additionally, in silico studies predicted excellent drug-like properties and the importance of triazole ring in stabilizing the complexation with target proteins. Overall, these results present compound 16 as a promising scaffold on which other molecules can be modeled to deliver new antimicrobial agents with improved potency. Graphic abstract: [Figure not available: see fulltext.].

Method for synthesizing asymmetric C-O coupled compound and application of asymmetric C-O coupled compound

The invention discloses a method for synthesizing an asymmetric C-O coupled compound and application of the asymmetric C-O coupled compound and belongs to the technical field of chemical synthesis. According to the method, a compound represented by a form

MONOAMINE OXIDASE INHIBITORS. THE SYNTHESIS AND EVALUATION OF A SERIES

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