59854-10-3Relevant articles and documents
Ni-Catalyzed C(sp3)–O Arylation of α-Hydroxy Esters
Monteith, John J.,Rousseaux, Sophie A. L.
supporting information, p. 9485 - 9489 (2021/12/09)
A Negishi cross-coupling of α-hydroxy ester derivatives and arylzinc reagents has been developed. This reaction tolerates both primary and secondary C(sp3)–O alcohol precursors and achieves efficient cross-coupling under Ni catalysis without the need for added external metal reductant, photocatalyst, or additives. The arylation of readily accessible C(sp3)–O electrophiles in this operationally simple, rapid, and mild reaction provides a complementary way of accessing desirable α-aryl ester products.
A mild, efficient, and inexpensive protocol for the selective deprotection of TBDMS ethers using KHSO4
Arumugam, Pandurangan,Karthikeyan, Ganesan,Perumal, Paramasivan T.
, p. 1146 - 1147 (2007/10/03)
Potassium hydrogensulfate in 30% aq. methanol deprotects a variety of tert-butyldimethylsilyl ethers at room temperature in excellent yields.
Antihypertensive agents
-
, (2008/06/13)
(Benzothiadiazine, benzamido and benzenesulfonyl)phenyl-substituted carboxyalkyl dipeptide compounds are disclosed. Compounds of this invention are useful as antihypertensive agents.
