59893-87-7

Basic information

• Product Name: 4,5-Dimethoxy-2-(2-propenyl)phenol
• Synonyms: 2-Allyl-4,5-dimethoxyphenol;4,5-Dimethoxy-2-(2-propenyl)phenol;4-Hydroxy-5-allylveratrole
• CAS NO: 59893-87-7
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 59893-87-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 38-41 °C
• Boiling Point: 313.926 °C at 760 mmHg
• Flash Point: 143.657 °C
• Appearance: /
• Density: 1.077±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 10.42±0.23(Predicted)
• CAS DataBase Reference: 4,5-Dimethoxy-2-(2-propenyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dimethoxy-2-(2-propenyl)phenol(59893-87-7)
• EPA Substance Registry System: 4,5-Dimethoxy-2-(2-propenyl)phenol(59893-87-7)

Safety Data

• Hazardous Substances Data: 59893-87-7(Hazardous Substances Data)

Usage

General Description

4,5-Dimethoxy-2-(2-propenyl)phenol, also known as eugenol, is a natural chemical compound found in various plants, including clove, basil, and cinnamon. It is commonly used in the production of perfumes, flavorings, and essential oils due to its pleasant aroma and flavor. Eugenol also possesses antimicrobial and antioxidant properties, making it a popular ingredient in dental products and as a natural preservative. Additionally, it has been studied for its potential anti-inflammatory and analgesic effects, leading to its use in traditional medicine for treating pain and inflammation. However,

Upstream product

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Downstream Products

• 19936-75-5 2-Allyl-5-methoxy-1,4-benzoquinone 
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• 65720-05-0 (E)-6-hydroxymethylisoeugenol 
• 101596-81-0 5,6-dimethoxy-3-phenyl-1H-indene 
• 78111-20-3 (2β,3β,3aα)-3,3a-dihydro-5-methoxy-3-methyl-3a-<3-<(methylsulfonyl)oxy>propyl>-2-(3,4,5-trimethoxyphenyl)-6(2H)-benzofuranone 
• 78095-16-6 4,5-dimethoxy-2-(phenylmethoxy)benzenepropanol methanesulfonate 

Relevant articles and documents

NEOLIGNANS FROM ANIBA LANCIFOLIA

The branches of the shrub Aniba lancifolia Kubitzki et Rodrigues (Lauraceae) contain besides 2-hydroxy-4,5-dimethoxyallylbenzene and its dimer cyclohexan-2-allyl-5-en-4,5-dimethoxy-4-O-(2'-allyl-4;,5'-dimethoxyphenyl)-1-one (lancilin, 2) 6 further novel n

Total synthesis of (-)-Haouamine B pentaacetate and structural revision of haouamine B

The enantiocontrolled total synthesis of (-)-haouamine B pentaacetate was accomplished via an optically active indane-fused β-lactam, which was prepared by a newly developed Friedel-Crafts reaction. Subsequent cleavage of the β-lactam and an intramolecular McMurry coupling reaction provided the core indane-fused tetrahydropyridine, which led to the elucidation of the structure, as proposed by Trauner and Zuba.

Design, synthesis, and docking of highly hypolipidemic agents: Schizosaccharomyces pombe as a new model for evaluating α-asarone-based HMG-CoA reductase inhibitors

A series of α-asarone-based analogues was designed by conducting docking experiments with published crystal structures of human HMG-CoA reductase. Indeed, synthesis and evaluation of this series showed a highly hypocholesterolemic in vivo activity in a murine model, as predicted by previous docking studies. In agreement with this model, the polar groups attached to the benzene ring could play a key role in the enzyme binding and probably also in its biological activity, mimicking the HMG-moiety of the natural substrate. The hypolipidemic action mechanism of these compounds was investigated by developing a simple, efficient, and novel model for determining HMG-CoA reductase inhibition. The partial purification of the enzyme from Schizosaccharomyces pombe allowed for testing of α-asarone- and fibrate-based analogues, resulting in positive and significant inhibitory activity.