59906-37-5

Basic information

• Product Name: N,N-dimethylthiophene-3-carboxamide
• Synonyms: N,N-dimethylthiophene-3-carboxamide
• CAS NO: 59906-37-5
• Molecular Formula: C₇H₉NOS
• Molecular Weight: 155.21746
• Mol File: 59906-37-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N-dimethylthiophene-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethylthiophene-3-carboxamide(59906-37-5)
• EPA Substance Registry System: N,N-dimethylthiophene-3-carboxamide(59906-37-5)

Safety Data

• Hazardous Substances Data: 59906-37-5(Hazardous Substances Data)

Usage

General Description

N,N-dimethylthiophene-3-carboxamide is a chemical compound that belongs to the class of amides. It is a derivative of thiophene, which is a five-membered heterocyclic compound containing sulfur. The presence of the dimethyl group on the nitrogen atom and the carboxamide moiety make this compound useful in various applications, including pharmaceuticals and agrochemicals. It has been studied for its potential antimicrobial and antifungal properties, as well as its use as a building block in organic synthesis. N,N-dimethylthiophene-3-carboxamide may also have potential as a corrosion inhibitor and as a component in electronic materials. Overall, this compound has diverse potential uses and applications in various industries.

Upstream product

• 872-31-1 3-Bromothiophene 
• 18503-89-4 N,N-dimethylformamide diisopropyl acetal 
• 6165-69-1 Thien-3-ylboronic acid 
• 13358-75-3 dimethylcarbamoyl iodide 
• 88-13-1 3-Thiophene carboxylic acid 
• 506-59-2 N,N-dimethylammonium chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 41507-35-1 3-thiophene carboxylic acid chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 130021-87-3 N,N-dimethyl-3-thiophenecarbothioamide 
• 32281-36-0 4,8-dihydrobenzo[1,2-b:4,5-b']dithiophene-4,8-dione 

Relevant articles and documents

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FeCl3 catalyzed amide compound synthesis method

The invention relates to an FeCl3 catalyzed amide compound synthesis method. According to the synthesis method, carboxylic acid and N-substituted formamide are employed to synthesize an amide compound under the catalysis of FeCl3. The synthesis method provided by the invention has the characteristics of mild conditions, high reaction efficiency, and wide applicability to substrates of different functional groups. The amide compound efficiently constructed by the invention is an important skeleton of many organic molecules, drugs, proteins and bioactive molecules. The synthesis method provided by the invention provides a widely applicable preparation method for synthesis of the compounds.

Pd/C as a catalyst for completely regioselective c=h functionalization of thiophenes under mild conditions

The completely C3-selective arylation of thiophenes and benzo[b]thiophenes was achieved by using Pd/C as a heterogeneous catalyst without ligands or additives under mild reaction conditions. The practicability of this transformation is demonstrated by notable functional group tolerance and the insensitivity of the reaction to H2O and air. This method is also applicable to nitrogen- and oxygen-containing heterocycles, yielding the corresponding C2-arylated products. Three-phase tests along with Hg-poisoning and hot-filtration tests suggest that the catalytically active species is heterogeneous in nature. I+ can do better! Pd/C can be used without ligands or additives to catalyze the completely C3-selective arylation of diversely substituted thiophenes and benzo[b]thiophenes under mild reaction conditions. The physical nature of the catalytic species was investigated and the mechanism was studied. Relative rate data generated in a "robustness screen" were used to design a complex substrate that undergoes highly chemoselective sequential functionalization. Copyright