60006-28-2Relevant articles and documents
Ytterbium triflate: A highly active catalyst for addition of amines to carbodiimides to N,N′,N″-trisubstituted guanidines
Zhu, Xuehua,Du, Zhu,Xu, Fan,Shen, Qi
, p. 6347 - 6349 (2009)
(Chemical Equation Presented) Ytterbium triflate was found to be efficient catalyst for addition of amines to carbodiimides to N,N′,N″- trisubstituted guanidines with a wide scope of amines under solvent-free condition.
Cyclic (Alkyl)amino Carbene Complex of Aluminum(III) in Catalytic Guanylation Reaction of Carbodiimides
Vardhanapu, Pavan K.,Bheemireddy, Varun,Bhunia, Mrinal,Vijaykumar, Gonela,Mandal, Swadhin K.
, p. 2602 - 2608 (2018/08/21)
Herein we report the synthesis of a cyclic (alkyl)amino carbene (cAAC) complex of AlMe3. This complex was used as an efficient catalyst for the guanylation reaction of carbodiimides with primary arylamines and secondary amines to deliver guanidine derivatives in good to excellent yields. This catalytic protocol can tolerate a wide range of functional groups. Furthermore, the longevity of the catalyst was tested in successive catalytic cycles, which indicated a sustained catalytic activity over a multiple cycles. The mechanistic pathway was well understood with the help of stoichiometric reaction and DFT study.
Enol-functionalized N-heterocyclic carbene lanthanide amide complexes: Synthesis, molecular structures and catalytic activity for addition of amines to carbodiimides
Li, Zhi,Xue, Mingqiang,Yao, Haisheng,Sun, Hongmei,Zhang, Yong,Shen, Qi
experimental part, p. 27 - 34 (2012/08/07)
Reaction of LnCl3 (Ln = Y, Nd, Sm and Yb) with enol-functionalized imidazolium salt H2LBr (L = 4-OMe-C 6H4COCH{C(NCHCHNiPr)}) and NaN(TMS)2 at a molar ratio of 1:4:1 in THF at room temperature afforded the corresponding novel enol-functionalized N-heterocyclic carbene (NHC) lanthanide amides L 2LnN(TMS)2 (Ln = Y (1), Nd (2), Sm (3), Yb (4)) in 37-40% yields. Molecular structures of 1-4 were determined by X-ray structure analyses. All complexes adopt monomeric structures where each 5-coordinated metal is coordinated by two NHC ligands and one amido group.in distorted trigonal bipyramid geometry. All complexes, especially Yb complex (4), were found to be highly active precatalysts for the catalytic addition of amines to carbodiimides giving guanidines. The system with 4 shows good functional group tolerance and a wide scope of amines including primary and secondary cyclic amines.