60012-49-9

Basic information

• Product Name: 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE
• Synonyms: 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE;2-(2-chloroethyl)piperidinium chloride;2-(2-Chloroethyl) piperidine hydrochloride
• CAS NO: 60012-49-9
• Molecular Formula: C₇H₁₄ClN*ClH
• Molecular Weight: 184.1067
• EINECS: 262-022-9
• Mol File: 60012-49-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 209.6 °C at 760 mmHg
• Flash Point: 80.6 °C
• Appearance: /
• Vapor Pressure: 0.201mmHg at 25°C
• CAS DataBase Reference: 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE(60012-49-9)
• EPA Substance Registry System: 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE(60012-49-9)

Safety Data

• Hazardous Substances Data: 60012-49-9(Hazardous Substances Data)

Usage

General Description

2-(2-chloroethyl)piperidinum chloride, also known as R 847, is a chemical compound that belongs to the class of piperidine derivatives. It is a quaternary ammonium salt with the molecular formula C8H17Cl2N and a molecular weight of 198.13 g/mol. 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE is commonly used as an intermediate in the synthesis of pharmaceuticals and organic chemicals. It is also used as a reactant in the preparation of various chemical compounds, such as quaternary ammonium compounds and ionic liquids. Additionally, 2-(2-chloroethyl)piperidinum chloride has potential applications in the fields of organic synthesis, drug development, and materials science. However, it is important to handle this compound with care, as it is a known irritant and should be used in a well-ventilated area and with appropriate personal protective equipment.

InChI:InChI=1/C7H14ClN.ClH/c8-5-4-7-3-1-2-6-9-7;/h7,9H,1-6H2;1H

Upstream product

• 1484-84-0 2(RS)-(2-hydroxyethyl)piperidine 
• 54160-32-6 α-methyl-2-piperidylcarbinol 
• 103-74-2 2-(2-Hydroxyethyl)pyridine 

Downstream Products

• 405315-50-6 alpha-(4-Bromophenyl)-2-(2-chloroethyl)-1-piperidineacetonitrile 
• 134291-23-9 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine-5-sulfone 
• 106939-04-2 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine-5-sulfoxide 
• 142154-41-4 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine 
• 134277-68-2 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylthio-10H-phenothiazine-5-sulfoxide 
• 134277-63-7 1-acetyl-6-(2-chloroethyl)-2-piperidinone 
• 134277-62-6 1-acetyl-2-(2-chloroethyl)piperidine 

Relevant articles and documents

Fe(III)-Catalyzed Aerobic Intramolecular N-N Coupling of Aliphatic Azides with Amines

An Fe(III)-catalyzed intramolecular N-N coupling of aliphatic azidoamines that forms diverse five- and six-membered semisaturated diazoheterocycles using air as an oxidant is reported, providing an alternative to hydrazine-based methods. Mechanistic studies suggest that a N-radical induced intramolecular homolytic substitution (SH2) is involved in ring closure. The power of this N-N bond-forming method is also demonstrated by using it as the final step in a total synthesis of (-)-newbouldine.

Octahydro-indolizine and quinolizine and hexahydro-pyrrolizine

The invention features substituted fused bicyclic compounds, pharmaceutical compositions containing them, and methods of using them to treat or prevent histamine-mediated diseases and conditions.

3-diphenyl substituted octahydroindolizine analgesic compounds

Octahydroindolizine compounds of formula (I): STR1 wherein Q is --NR--, --(CH2)z --, --CH=CH--, --C C--, --OCH2 --, --SCH2 --, --SO2 --, --SO--, --CO--, or an oxygen or a sulfur atom and where R, R1 and R2 are substituents such as alkyl and x, y and z are independently the integers 0-3. Also, pharmaceutical compositions containing (I), intermediates and methods for treating pain.