60028-86-6

Basic information

• Product Name: 3,4-dimethoxy-N-methylbenzamide
• Synonyms: 3,4-dimethoxy-N-methylbenzamide
• CAS NO: 60028-86-6
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.21512
• Mol File: 60028-86-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-dimethoxy-N-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxy-N-methylbenzamide(60028-86-6)
• EPA Substance Registry System: 3,4-dimethoxy-N-methylbenzamide(60028-86-6)

Safety Data

• Hazardous Substances Data: 60028-86-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 2169-98-4 3,4-Dimethoxy-benzaldehyde oxime 
• 593-51-1 methylamine hydrochloride 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 93-07-2 Veratric acid 
• 1326101-69-2 N-(4-(dimethylamino)benzyl)-3,4-dimethoxy-N-methylbenzamide 
• 74-89-5 methylamine 
• 421-20-5 Methyl fluorosulfonate 
• 2024-83-1 veratronitrile 
• 82463-72-7 2-bromo-4,5-dimethoxy-N-methylbenzenemethanamine 
• 67-64-1 acetone 

Downstream Products

• 52050-44-9 5-methyl-8,9-dimethoxy-6(5H)-phenanthridone 
• 1613319-89-3 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 2-naphthoate 
• 1613319-88-2 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 2-iodobenzoate 
• 1613319-87-1 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 3-chlorobenzoate 
• 1613319-86-0 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 3-iodobenzoate 
• 1613319-85-9 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-nitrobenzoate 
• 1613319-84-8 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-(trifluoromethyl)benzoate 
• 1613319-83-7 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-fluorobenzoate 
• 1613319-82-6 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-bromobenzoate 
• 1613319-81-5 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-iodobenzoate 
• 1613319-80-4 4,5-dimethoxy-2-(methylcarbamoyl)phenyl benzoate 
• 1613319-79-1 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-methylbenzoate 
• 1613319-78-0 4,5-dimethoxy-2-(methylcarbamoyl)phenyl 4-chlorobenzoate 
• 2041-27-2 2,3-Dimethoxyfluoren-9-one 

Relevant articles and documents

Tandem Transformation of Aldoximes to N-Methylated Amides Using Methanol

Tandem conversion of aldoximes to N-methylated amides with methanol in presence of a single Ru(II) catalyst is accomplished through the Ru(II)-mediated rearrangement followed by the reductive N-methylation. Employing this protocol, several aldoximes were directly transformed to the N-methylated amides using methanol. Kinetic experiments with H218O advocated that the aldoxime is acted as the nucleophile during the aldoxime to amide rearrangement process. Involvement of nitrile intermediate during this transformation is realized from the kinetic study. (Figure presented.).

Metal-free aryltrifluoromethylation of activated alkenes

Metal-free: The first metal-free aryltrifluoromethylation of activated alkenes has been developed. With this method, trifluoromethylated isoquinolinediones, spirobicycles, oxindoles, and α-aryl-β- trifluoromethylamides were obtained with high control of the regioselectivity. Copyright

Hansch analysis of veratric acid derivatives as antimicrobial agents

The synthesis, characterization and antimicrobial evaluation of a new series of veratric acid derivatives are presented. Preliminary in vitro antimicrobial activity of the title compounds was assessed against a panel of microorganisms including Gram-positive and Gram-negative bacteria and fungi. Some of the veratric acid derivatives exhibited significant in vitro antimicrobial activity. QSAR investigation applied to find a correlation between different physicochemical parameters of the veratric acid derivatives and their antimicrobial activity indicated the importance of topological parameters in describing the antimicrobial activity.