60083-15-0

Basic information

• Product Name: Butanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester, (Z)-
• CAS NO: 60083-15-0
• Molecular Formula: C12H14N2O3
• Molecular Weight: 234.255
• Mol File: 60083-15-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester, (Z)-(60083-15-0)
• EPA Substance Registry System: Butanoic acid, 3-oxo-2-(phenylhydrazono)-, ethyl ester, (Z)-(60083-15-0)

Safety Data

• Hazardous Substances Data: 60083-15-0(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 100-34-5 benzene diazonium chloride 
• 62-53-3 aniline 
• 297766-64-4 1,3-Diphenyltriazen 

Downstream Products

• 132934-86-2 5-Acetyl-3-phenyl-2-[(Z)-phenylimino]-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 89516-24-5 ethyl 5-cyano-4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate 
• 125058-25-5 5-Cyano-4-((E)-2-furan-2-yl-vinyl)-6-oxo-1-phenyl-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-86-0 5-Cyano-4-[(E)-2-(4-methoxy-phenyl)-vinyl]-6-oxo-1-phenyl-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-97-3 5-Cyano-6-oxo-1-phenyl-4-(2-piperidin-1-yl-ethyl)-1,6-dihydro-pyridazine-3-carboxylic acid ethyl ester 
• 125040-92-8 ethyl-5-amino-6-cyano-7-(2-furyl)-4-oxo-3-phenyl-3,4-dihydro-1-phthalazinecarboxylate 
• 125040-91-7 5-Amino-6-cyano-7-(4-methoxy-phenyl)-4-oxo-3-phenyl-3,4-dihydro-phthalazine-1-carboxylic acid ethyl ester 
• 60083-22-9 ethyl (2E)-3-oxo-2-(2-phenylhydrazinylidene)butanoate 
• 135587-62-1 4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid ethyl ester 
• 859296-96-1 4-methyl-6-oxo-1-phenyl-1,6-dihydro-pyridazine-3-carbonyl chloride 
• 412339-20-9 4-methyl-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylic acid 
• 132935-08-1 5-{1-[(2,4-Dinitro-phenyl)-hydrazono]-ethyl}-3-phenyl-2-[(Z)-phenylimino]-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 132935-06-9 5-{1-[(4-Nitro-phenyl)-hydrazono]-ethyl}-3-phenyl-2-[(Z)-phenylimino]-2,3-dihydro-[1,3,4]thiadiazin-6-one 
• 132934-98-6 5-{1-[(2,4-Dinitro-phenyl)-hydrazono]-ethyl}-3-phenyl-2-thioxo-2,3-dihydro-[1,3,4]thiadiazin-6-one 

Relevant articles and documents

Sydnone derivatives. Part VII: Synthesis of some novel thiazoles and their pharmacological properties

The synthesis of some 4-(arylsydnonyl)-2- (4-arylhydrazono-3-methyl-5-oxo-2-pyrazolin-1-yl)-thiazoles by reacting 1-thiocarboxamido-3-methyl-4-(arylhydrazono)-2-pyrazolin-5-ones with different 4-bromoacetyl-3-arylsydnones is described. A few compounds from this series were screened for their anti-inflammatory, analgesic, and CNS depressant activities. Among the tested compounds 6s, 6d, 6n, and 6u showed significant anti-inflammatory activity comparable with that of standard drug Ibuprofen. Compounds containing chlorine and carboxylic substituents are more active. 6f, 6r, and 6u showed marked analgesic activity and most of the compounds tested showed promising CNS depressant activity comparable with that of standard drug pentobarbitone.

A microwave assisted diazo coupling reaction: The synthesis of alkylazines and thienopyridazines

Heating diazoaminobenzene with active methylene compounds 1-3 in microwave oven in acetic acid, in the presence of hydrochloric acid, afforded the corresponding arylhydrazones 5-7. These reaction products were condensed with ethyl cyanoacetate in a domestic microwave oven after 1-2 minutes heating to yield the pyridazinones 8-12. Compounds 8c and 12 reacted with sulfur in basic DMF solution, in microwave oven using MORE technology to yield the thienopyridazinone 14 and 16 respectively. While 17 was produced when 8b was treated like wise with sulfur and DMF in the presence of piperidine. Compounds 16 coupled with aromatic diazonium salts to yield arylazo derivatives 21a-c. Copyright Taylor & Francis Group, LLC.

Synthesis, characterization and antimicrobial studies of some novel 3- arylazo-7-hydroxy-4-methylcoumarins

A series of 3-arylazo-7-hydroxy-4-methylcoumarins have been synthesized in excellent yields (80-90%) and their structures established on the basis of IR, 1H NMR, mass spectral data and elemental analyses. Their purity has been ascertained by ch