60135-00-4

Basic information

• Product Name: methyl 3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1′-biphenyl]-2-carboxylate
• Synonyms: methyl 3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1′-biphenyl]-2-carboxylate
• CAS NO: 60135-00-4
• Molecular Weight: 244.29
• Mol File: 60135-00-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1′-biphenyl]-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1′-biphenyl]-2-carboxylate(60135-00-4)
• EPA Substance Registry System: methyl 3-methyl-5-oxo-1,2,5,6-tetrahydro-[1,1′-biphenyl]-2-carboxylate(60135-00-4)

Safety Data

• Hazardous Substances Data: 60135-00-4(Hazardous Substances Data)

Upstream product

• 2538-76-3 1,1'-benzylidenedipiperidine 
• 105-45-3 acetoacetic acid methyl ester 
• 100-52-7 benzaldehyde 

Downstream Products

• 5337-88-2 3-methyl-5-phenyl-2-cyclohexen-1-one 
• 1258974-95-6 methyl 2,3-dimethyl-4-oxo-6-phenyl-2-cyclohexenecarboxylate 
• 1316834-14-6 C₁₅H₁₄O₄ 

Relevant articles and documents

The use of Hagemann's Esters to prepare highly functionalized phenols and benzenes

Hagemann's esters can be converted into highly functionalized phenols or arenes. The systematic functionalization of Hagemann's ester derivatives permits the preparation of tri-and tetraalkyl-substituted phenols or tetra-, penta-, and hexaalkyl-substituted benzenes. Kotnis's aromatization procedure was found to be solvent dependent, and Suzuki couplings were found to be sensitive to steric hindrance. Wittig olefination and ortho-Claisen reactions were reliable means to introduce alkyl substituents at C-4 and/or C-5 positions, respectively. The acid-promoted dehydration of tertiary alcohol 46 to produce enone 47, followed by its selective alkylation (cf. 48) is new. ARKAT USA, Inc.

A Novel, One Pot Synthesis of 4-Carbalkoxy-3-methyl-5-substitutedphenyl-2-cyclohexen-1-ones

A novel, one pot synthesis of 4-carbalkoxy-3-methyl-5-substitudedphenyl-2-cyclohexen-1-ones (1-8) has been achieved by reacting appropriately substituted benzaldehyde with methyl or ethyl acetoacetate in presence of piperidine in ethanol.The structures (1