60148-13-2 Usage
Description
2-Isocyanomethylpridine is an organic compound characterized by the presence of an isocyanomethyl group attached to a pyridine ring. It is known for its reactivity and versatility in chemical synthesis, making it a valuable building block for various applications.
Uses
Used in Pharmaceutical Industry:
2-Isocyanomethylpridine is used as a synthetic reagent for the creation of azaindolizines, which are compounds with two nitrogen atoms in a 5-membered ring. These azaindolizines are of significant interest in the pharmaceutical industry due to their potential applications as therapeutic agents, particularly in the development of novel drugs targeting various diseases and conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Isocyanomethylpridine serves as a key intermediate for the production of various organic compounds. Its unique structure allows for a range of reactions, including cyclization, substitution, and addition reactions, which can be harnessed to synthesize a diverse array of molecules with different properties and applications.
Used in Research and Development:
2-Isocyanomethylpridine is also utilized in research and development settings, where it can be employed to explore new synthetic pathways and develop innovative chemical processes. Its reactivity and structural features make it an attractive candidate for the design and synthesis of new molecules with potential applications in various industries, including pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 60148-13-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,4 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 60148-13:
(7*6)+(6*0)+(5*1)+(4*4)+(3*8)+(2*1)+(1*3)=92
92 % 10 = 2
So 60148-13-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2/c1-8-6-7-4-2-3-5-9-7/h2-5H,6H2
60148-13-2Relevant articles and documents
Formation of Imidazopyridines by the Phase Transfer Catalyzed Reaction of α-(Aminomethyl)pyridines with CHCl3 and Alkaline Hydroxide
Langry, Kevin C.
, p. 2400 - 2404 (2007/10/02)
The reaction of chloroform with 2-(aminomethyl)pyridine (1) under basic phase-transfer catalysis affords the highly fluorescent imidazopyridine (2) in 25percent isolated yield.Despite the formation of considerable tarry residue, GC-MS indicates that the volatile fraction of the reaction is simple and consists of 2 and two minor components identified as N-(2-pyridylmethyl)formamide (6) and (2-pyridylmethyl)isonitrile (7).The basic phase transfer catalyzed reaction of chloroform with a series of α-(aminomethyl)azanaphthalenes was found to be general and yield the corresponding annulated imidazo derivatives in comparable yields.Despite product yields in the 25percent range, GC of the reaction mixtures indicates that the volatile fractions generally consist of residual starting aminomethyl compound, the imidazo product, and a minor amount of the (α-azanaphthylmethyl)formamide.However, 3-(aminomethyl)isoquinoline (18) failed to provide any of the expected imidazoisoquinoline (19).The failure to detect 19 was investigated.
