60201-23-2

Basic information

• Product Name: Propanoic acid, 3,3,3-trifluoro-2-methyl-2-(4-phenoxyphenoxy)-, methyl ester
• CAS NO: 60201-23-2
• Molecular Formula: C17H15F3O4
• Molecular Weight: 340.299
• Mol File: 60201-23-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3,3,3-trifluoro-2-methyl-2-(4-phenoxyphenoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3,3,3-trifluoro-2-methyl-2-(4-phenoxyphenoxy)-, methyl ester(60201-23-2)
• EPA Substance Registry System: Propanoic acid, 3,3,3-trifluoro-2-methyl-2-(4-phenoxyphenoxy)-, methyl ester(60201-23-2)

Safety Data

• Hazardous Substances Data: 60201-23-2(Hazardous Substances Data)

Upstream product

• 337-16-6 2-hydroxy-2-methyl-3,3,3-trifluoropropionic acid methyl ester 
• 59696-22-9 4-(4-phenoxy)phenyl-2-thienyliodonium chloride 
• 60201-24-3 (+/-)-2-(4-phenoxyphenoxy)-3,3,3-trifluoro-2-methylpropionic acid 

Downstream Products

• 60201-24-3 (+/-)-2-(4-phenoxyphenoxy)-3,3,3-trifluoro-2-methylpropionic acid 

Relevant articles and documents

Analogues of clofibrate and clobuzarit containing fluorine in the side chains

A series of analogues of clofibrate and 2-[4-(4-chlorophenyl)phenylmethoxy]-2-methylpropionic acid (clobuzarit) has been prepared by replacing the methyl groups by trifluoromethyl groups and changing the aromatic moiety. The activity of these compounds has been assayed on the plasma levels of cholesterol, Total Esterified Fatty Acids (T.E.F.A.) and fibrinogen in rats. It appears that derivatives of the first series which contain only one trifluoromethyl group are hypocholesterolaemic and that many mono- of bis- trifluoromethyl derivatives of the second series lower the levels of both cholesterol and T.E.F.A. in contrast to clobuzarit.

Substituted aryloxy-3,3,3-trifluoro-2-propionic acids, esters and salts thereof

Derivatives of 2-hydroxy-3,3,3-trifluoro-2-(alkyl or trifluoromethyl)propionic acid bearing a phenyl or naphthyl group linked to the 2-hydroxy group either directly or via an intermediate methylene group. The compounds reduce the concentrations of cholesterol, total esterified fatty acids or fibrinogen in the blood plasma of test animals and some compounds show anti-arthritic properties.