6026-65-9

Basic information

• Product Name: (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al
• Synonyms: (18R)-14,18-Epoxy-5-oxoophiobola-3,7,19-trien-25-al;(18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al;Anhydroophiobolin;Anhydroophiobolin A;14,17- Epoxy-5-oxo-3, 7, 18-ophiobolatrien-21-al
• CAS NO: 6026-65-9
• Molecular Formula: C25H34O3
• Molecular Weight: 382.53566
• Mol File: 6026-65-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 136 °C
• Boiling Point: 520.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al(CAS DataBase Reference)
• NIST Chemistry Reference: (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al(6026-65-9)
• EPA Substance Registry System: (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al(6026-65-9)

Safety Data

• Hazardous Substances Data: 6026-65-9(Hazardous Substances Data)

Usage

Description

(18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al is a complex organic compound derived from the ophiobolin family of fungal metabolites. It is characterized by its unique molecular structure, which includes a 5-oxo group, a 14,18-epoxy bridge, and a 3,4-didehydro functionality. (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al exhibits a broad range of biological activities, making it a promising candidate for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
(18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al is used as a pharmaceutical agent for its cytotoxic properties. It has been found to be effective against HepG2 and K562 cancer cells, with IC50s of 55.7 and 39.5 μM, respectively. This makes it a potential candidate for the development of new anticancer drugs.
Used in Agricultural Industry:
As a member of the ophiobolin complex, (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al possesses antibacterial, antifungal, and nematocidal activities. It can be used as a biopesticide to control various pests and diseases in agriculture, reducing the reliance on chemical pesticides and promoting sustainable farming practices.
Used in Environmental Applications:
The herbicidal properties of (18R)-5-Oxo-14,18-epoxy-3,4-didehydroophiobola-7,19-diene-25-al make it a potential candidate for the development of new, environmentally friendly herbicides. These could be used to control unwanted plant growth in various settings, such as agriculture, forestry, and urban areas, without causing significant harm to the environment or non-target organisms.