6026-73-9

Basic information

• Product Name: 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene
• CAS NO: 6026-73-9
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.1998
• Mol File: 6026-73-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 269.6°C at 760 mmHg
• Flash Point: 113.9°C
• Density: 1.117g/cm³
• Vapor Pressure: 0.0119mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene(6026-73-9)
• EPA Substance Registry System: 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene(6026-73-9)

Safety Data

• Hazardous Substances Data: 6026-73-9(Hazardous Substances Data)

Usage

Description

1-(2-methylprop-1-en-1-yl)-3-nitrobenzene, also known as para-methylallyl nitrobenzene, is an organic compound characterized by its chemical formula C10H11NO2. It presents as a pale yellow liquid with a distinct strong, sweet, and floral odor. 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene is derived from nitrobenzene and 2-methylprop-1-en-1-ol through a chemical reaction process.

Uses

Used in Fragrance Industry:
1-(2-methylprop-1-en-1-yl)-3-nitrobenzene is used as a fragrance and flavoring agent for its strong, sweet, and floral scent. It is particularly favored in the production of perfumes, soaps, and other scented products due to its appealing odor and ability to enhance the overall fragrance profile of these products.
Used in Chemical Synthesis:
In addition to its applications in the fragrance industry, 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene is also utilized in chemical synthesis. It serves as a key intermediate for creating other organic compounds, contributing to the diversity of chemical products available for various industries.
Safety Precautions:
It is crucial to handle 1-(2-methylprop-1-en-1-yl)-3-nitrobenzene with care due to its toxic nature. Prolonged exposure to this compound may result in skin and eye irritation, as well as respiratory problems. Therefore, proper safety measures, including the use of personal protective equipment and adherence to safety guidelines, are essential when working with this compound.

Upstream product

• 585-79-5 m-nitrobromobenzene 
• 115-11-7 isobutene 
• 121-73-3 3-Nitrochlorobenzene 
• 611-70-1 phenyl isopropyl ketone 
• 619-25-0 3-Nitrobenzyl alcohol 
• 513-35-9 2-methyl-but-2-ene 
• 586-39-0 1-nitro-3-vinyl-benzene 
• 24470-78-8 isopropyltriphenylphosphonium iodide 
• 99-61-6 3-nitro-benzaldehyde 
• 5912-95-8 α-(1-methylethyl)-3-nitrobenzenemethanol 
• 3958-63-2 lithium 2-nitropropane 
• 86096-88-0 m-nitrobenzyl mesitoate 

Downstream Products

• 153624-73-8 3-(2-methylprop-1-en-1-yl)aniline 
• 1218792-57-4 C₁₁H₁₄N₂O₃ 
• 131826-11-4 3-isobutylaniline 
• 75189-01-4 2-Amino-m-nitroisobutyrophenon-phenylhydrazon-hydrochlorid 
• 75189-22-9 2-Amino-m-nitroisobutyrophenon-hydrochlorid 
• 75189-08-1 3-Anilino-4-hydroxy-5,5-dimethyl-4-(m-nitrophenyl)imidazolidin-2-on 
• 75189-20-7 anti(E)-2-Amino-m-nitroisobutyrophenonoxim 
• 119273-92-6 2-methoxy-2-methyl-1-(3'-nitrophenyl)propane 
• 179251-16-2 N-(2,2-dimethyl-1-oxopropyl)-3-(2-methyl-1-propenyl)aniline 

Relevant articles and documents

Production of [...] (by machine translation)

Useful as an intermediate for the production of a horticultural [to] acaricidal agent can provide an industrially advantageous method for producing 3 - [...]. [Solution] nitro bromobenzene isobutene and the like, a palladium catalyst, a phosphine-based coordination, bases, solvents, and the auxiliary agent in the presence of reaction, isobutene was added to compound, the additional compound is isolated or not isolated, hydrogenation (catalytic reduction) by the production method 3 - [...] or salts thereof. [Drawing] no (by machine translation)

Discovery of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24 h bronchodilatory efficacy

Compound 4p was identified from a series of 6-hydroxy-4H-benzo[1,4]oxazin-3-ones as potent agonist of the human β2-adrenoceptor with a high β1/β2-selectivity. A complete reversal of acetylcholine-induced bronchoconstrictio

Biphenylsulfonamide endothelin antagonists: Structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N-(3,4- dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1,1'-biphenyl]-2-sulfonamide (BMS- 187308)

Substitution at the ortho position of N-(3,4-dimethyl-5-isoxazolyl) benzenesulfonamide led to the identification of the biphenylsulfonamides as a novel series of endothelin-A (ETA) selective antagonists. Appropriate substitutions on the pendant phenyl ring led to improved binding as well as functional activity. A hydrophobic group such as isobutyl or isopropoxyl was found to be optimal at the 4'-position. Introduction of an amino group at the 2'-position also led to improved analogues. Combination of the optimal 4'- isobutyl substituent with the 2'-amino function afforded an analogue (20, BMS-187308) with improved ET(A) binding affinity and functional activity. Compound 20 also has good oral activity in inhibiting the pressor effect caused by an ET-1 infusion in rats. Doses of 10 and 30 μmol/kg iv 20 attenuated the pressor responses due to the administration of exogenous ET-1 to conscious monkeys, indicating that the compound inhibits the in vivo activity of endothelin-1 in nonhuman primates.