6029-86-3

Basic information

• Product Name: LATIFOLINE
• Synonyms: LATIFOLINE;(2R)-Tetrahydro-3β-hydroxy-2α,4α-dimethyl-5-oxofuran-3-carboxylic acid [[(7R,7aR)-5,6,7,7a-tetrahydro-7-[(Z)-2-methyl-2-butenoyloxy]-3H-pyrrolizin]-1-yl]methyl ester
• CAS NO: 6029-86-3
• Molecular Formula: C20H27NO7
• Molecular Weight: 393.43088
• Mol File: 6029-86-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 538.3°Cat760mmHg
• Flash Point: 279.3°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 7.85E-14mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: LATIFOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: LATIFOLINE(6029-86-3)
• EPA Substance Registry System: LATIFOLINE(6029-86-3)

Safety Data

• Hazardous Substances Data: 6029-86-3(Hazardous Substances Data)

Usage

Description

LATIFOLINE is an alkaloid derived from the bark of Funturnia latifolia Stapf. It crystallizes from MeOH with a melting point of 162-6°C and from Me2CO with a melting point of 129°C. The natural base is laevorotatory with [α]D4.0° (c 0.8, CHCI3), while the synthetic optically inactive form has a melting point of 170.5-171.5°C. A crystalline acetyl derivative has been prepared with a melting point of 160°C and [α]D 15° (c 1.2, CHCI3). The structure has been confirmed through spectroscopic evidence as 5-conanen-3-ol.

Uses

1. Used in Pharmaceutical Industry:
LATIFOLINE is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: LATIFOLINE is used as a pharmaceutical compound for its potential therapeutic applications.
2. Used in Research and Development:
LATIFOLINE is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules. The expression is: LATIFOLINE is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules.
3. Used in Drug Synthesis:
LATIFOLINE can be used as a starting material or intermediate in the synthesis of other pharmaceutical compounds. The expression is: LATIFOLINE is used as a starting material or intermediate in the synthesis of other pharmaceutical compounds.
4. Used in Quality Control and Standardization:
LATIFOLINE can be used as a reference compound for quality control and standardization of pharmaceutical products containing this alkaloid. The expression is: LATIFOLINE is used as a reference compound for quality control and standardization of pharmaceutical products containing this alkaloid.

References

Janot, Khuong Huu, Goutarel., Cornpt. rend., 254, 1326 (1962) Nagata, Terasawa, Aoki., Tetrahedron Lett., 869 (1963)

InChI:InChI=1/C20H27NO7/c1-5-11(2)17(22)28-15-7-9-21-8-6-14(16(15)21)10-26-19(24)20(25)12(3)18(23)27-13(20)4/h5-6,12-13,15-16,25H,7-10H2,1-4H3/b11-5-/t12-,13-,15-,16-,20+/m1/s1