60312-95-0

Basic information

• Product Name: 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one
• Synonyms: 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one;1-[4'-Bromo[1,1'-biphenyl]-4-yl]-2-phenylethanone;Einecs 262-161-5;1-(4'-broMobiphenyl-4-yl)-2-(cyclohexa-2,4-dienyl)ethanone
• CAS NO: 60312-95-0
• Molecular Formula: C₂₀H₁₅BrO
• Molecular Weight: 351.2365
• EINECS: 262-161-5
• Mol File: 60312-95-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one(60312-95-0)
• EPA Substance Registry System: 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one(60312-95-0)

Safety Data

• Hazardous Substances Data: 60312-95-0(Hazardous Substances Data)

Usage

Description

1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one is a complex chemical compound that features a 1-phenyl-2-benzylidene acetone core with a 4'-bromo[1,1'-biphenyl]-4-yl group attached. It is a member of the ketone class and is known for its unique structural characteristics and reactivity.

Uses

Used in Organic Synthesis:
1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one is used as an intermediate in organic synthesis for its ability to contribute to the formation of more complex organic molecules, making it a valuable component in the creation of various chemical products.
Used in Chemical Research:
1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one serves as a subject of study in chemical research, where its reactivity and structural features are explored to understand its potential applications and to develop new methods for synthesizing related compounds.
Used in Pharmaceutical Industry:
1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one is used as a building block in the pharmaceutical industry for its potential to be incorporated into the development of new drugs, leveraging its unique structure to target specific biological pathways.
Used in Agrochemicals:
In the agrochemical industry, 1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one is used as a chemical component in the development of pesticides and other agricultural chemicals, where its structural properties can be exploited for targeted pest control.
Used in Materials Science:
1-(4'-bromo[1,1'-biphenyl]-4-yl)-2-phenylethan-1-one is also utilized in materials science as a component in the synthesis of new materials with specific properties, such as those with enhanced stability or reactivity for various applications.

Upstream product

• 92-66-0 4-bromo-1,1'-biphenyl 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 60313-01-1 3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-one 
• 56181-82-9 (+/-)-cis/trans-3-(4''-Bromobiphenyl-4'-yl)-1,2,3,4-tetrahydronaphthalen-1-ol 
• 70942-04-0 1-Bromo-3-(4'-bromo-biphenyl-4-yl)-1,2,3,4-tetrahydro-naphthalene 
• 124325-90-2 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid ethyl ester 
• 124325-89-9 3-(4'-Bromo-biphenyl-4-yl)-4-phenyl-butyric acid 
• 60313-31-7 4-bromo-4'-(1-bromo-2-phenylethyl)-1,1'-biphenyl 
• 60313-47-5 {1-[4'-bromo(1,1'-biphenyl)-4-yl]-2-phenylethyl}malonic acid 
• 124325-88-8 3-(4'-bromo-biphenyl-4-yl)-3-hydroxy-4-phenyl-butyric acid ethyl ester 
• 60313-17-9 4'-bromo-α-(phenylmethyl)(1,1'-biphenyl)-4-methanol 

Relevant articles and documents

Synthesis and antitumor activity of 4-hydroxycoumarin derivatives

A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity against five human tumor cell lines. A series of 4-hydroxycoumarin derivatives was prepared and evaluated for antitumor activity. The key fragments were 2a-c, 5c, 12b, 13b, 17, and 18 which were prepared via dianion ring cyclization, Friedel-Crafts acylation, and Reformatsky reaction. Compound 20b showed the most potent antitumor activity among the total 12 derivatives and compounds 19a and 19b exhibited efficacy comparable to etoposide in vitro antitumor activity.