60329-03-5Relevant articles and documents
Geometrical Isomerism in Guanabenz Free Base: Synthesis, Characterization, Crystal Structure, and Theoretical Studies
Kathuria, Deepika,Chourasiya, Sumit S.,Wani, Aabid Abdullah,Singh, Manjeet,Sahoo, Subash C.,Bharatam, Prasad V.
, p. 3183 - 3191 (2019)
Guanabenz is a drug used for the treatment of hypertension, and it exhibits isomerism and tautomerism. In this article, X-ray diffraction studies (single crystal and powder) as well as thermochemical analysis on the guanabenz have been reported. The resul
2-alkylidene-aminoguanidines and methods of use therefor
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, (2008/06/13)
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging) which contain 2-alkylidene aminoguanidines and derivatives thereof. Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.