60384-30-7 Usage
Description
3α,7β-Diacetoxy-5β-cholan-24-oic acid methyl ester is a chemical compound derived from the modification of the naturally occurring bile acid, ursodeoxycholic acid. It is characterized by the presence of two acetyl groups at the 3α and 7β positions, and a methyl ester group at the 24th position. 3α,7β-Diacetoxy-5β-cholan-24-oic acid methyl ester exhibits unique structural features that make it a valuable intermediate in the synthesis of various bile acid derivatives and metabolites.
Uses
Used in Pharmaceutical Industry:
3α,7β-Diacetoxy-5β-cholan-24-oic acid methyl ester is used as a reactant for the preparation of bile acids and their metabolites. It plays a crucial role in the synthesis of novel bile acid-based therapeutic agents, which have potential applications in the treatment of various liver diseases, cholesterol-related disorders, and other health conditions.
Used in Chemical Research:
3α,7β-Diacetoxy-5β-cholan-24-oic acid methyl ester serves as an important intermediate in the development of new chemical entities and the study of bile acid chemistry. It can be used to explore the structure-activity relationships of bile acids and their derivatives, leading to the discovery of new compounds with improved pharmacological properties and therapeutic potential.
Used in Drug Development:
3α,7β-Diacetoxy-5β-cholan-24-oic acid methyl ester is utilized in the design and development of innovative drug candidates targeting various diseases and conditions. Its unique structural features allow for the creation of new molecules with enhanced efficacy, selectivity, and safety profiles, making it a valuable asset in the field of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 60384-30-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,3,8 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 60384-30:
(7*6)+(6*0)+(5*3)+(4*8)+(3*4)+(2*3)+(1*0)=107
107 % 10 = 7
So 60384-30-7 is a valid CAS Registry Number.
60384-30-7Relevant articles and documents
Preparation method of 3beta-ursodesoxycholic acid
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, (2019/07/04)
The invention discloses a synthesis method of 3beta-ursodesoxycholic acid. The method comprises following steps: ursodesoxycholic acid is taken as a raw material and subjected to esterification, 3-position and 7-position hydroxyl groups, selective removal of a 3-position protecting group, oxidization of the 3-position hydroxyl group, reduction into 3beta hydroxyl group and hydrolysis of 7-positionand 24-position hydroxyl groups, and 3beta-ursodesoxycholic acid is obtained. The synthesis method is novel, lower in cost, high in yield, simple and convenient to operate and environmentally friendly, and conditions are mild.
Novel derivatives of 3α,7α-dihydroxy-5β-cholan-24-oic acid (chenodeoxycholic acid) and 3α,7β-dihydroxy-5β-cholan-24-oic acid (ursodeoxycholic acid)
Kritchevsky,Poli,Scolastico,Sirtori
, p. 41 - 48 (2007/10/02)
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