604-80-8

Basic information

• Product Name: ISORHAMNETIN-3-RUTINOSIDE
• Synonyms: NARCISIN;NARCISSIN;ISORHAMNETIN-3-O-RUTINOSIDE;ISORHAMNETIN-3-RUTINOSIDE;4h-benzopyran-4-one,3-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyran;7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-osyl)oxy)-;isorhamnetin3-beta-rutinoside;isorhamnetin3-rhamnoglucoside
• CAS NO: 604-80-8
• Molecular Formula: C₂₈H₃₂O₁₆
• Molecular Weight: 624.54
• Product Categories: Flavanols;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 604-80-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 182-184°C
• Boiling Point: 953.1 °C at 760 mmHg
• Flash Point: 312.9 °C
• Appearance: /
• Density: 1.74
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.728
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 6.17±0.40(Predicted)
• CAS DataBase Reference: ISORHAMNETIN-3-RUTINOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ISORHAMNETIN-3-RUTINOSIDE(604-80-8)
• EPA Substance Registry System: ISORHAMNETIN-3-RUTINOSIDE(604-80-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 604-80-8(Hazardous Substances Data)

Usage

Description

ISORHAMNETIN-3-RUTINOSIDE, also known as Narcissoside, is a flavonoid derived from Nitraria tangutorum. It is a yellow powder with potential antiproliferative activity, particularly in human colon cancer cell lines such as HT29.

Uses

Used in Pharmaceutical Industry:
ISORHAMNETIN-3-RUTINOSIDE is used as a pharmaceutical compound for its potential antiproliferative activity. It is being studied for its effects on human colon cancer cell lines, such as HT29, where it may help inhibit the growth and proliferation of cancer cells.
Used in Cancer Research:
In the field of cancer research, ISORHAMNETIN-3-RUTINOSIDE is used as a subject of investigation for its potential role in cancer treatment. Its antiproliferative properties make it a promising candidate for further research into developing new therapeutic strategies against colon cancer and possibly other types of cancer.
Used in Drug Development:
ISORHAMNETIN-3-RUTINOSIDE may be utilized in the development of new drugs targeting cancer cells. Its chemical properties and biological activities are of interest to researchers and pharmaceutical companies seeking to create novel and effective treatments for various types of cancer, including colon cancer.
Used in Nutraceutical Industry:
Due to its natural origin and potential health benefits, ISORHAMNETIN-3-RUTINOSIDE may also find application in the nutraceutical industry. It could be incorporated into dietary supplements or functional foods that aim to support overall health and well-being, particularly in relation to cancer prevention and management.

InChI:InChI=1/C28H32O16/c1-9-18(32)21(35)23(37)27(41-9)40-8-16-19(33)22(36)24(38)28(43-16)44-26-20(34)17-13(31)6-11(29)7-15(17)42-25(26)10-3-4-12(30)14(5-10)39-2/h3-7,9,16,18-19,21-24,27-33,35-38H,8H2,1-2H3/t9-,16-,18-,19-,21+,22+,23+,24-,27+,28+/m1/s1

Downstream Products

• 3615-41-6 L-Rhamnose 
• 50-99-7 D-glucose 
• 480-19-3 isorhamnetin 
• 6743-92-6 isorhamnetin-3-O-glucoside 
• 120374-34-7 Acetic acid 7-acetoxy-2-(4-acetoxy-3-methoxy-phenyl)-4-oxo-3-[(2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-((2R,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-4H-chromen-5-yl ester 
• 10257-28-0 D-Galactose 
• 73-34-7 L-rhamnose 
• 26184-96-3 rutinose 

Relevant articles and documents

Flavonoid and benzophenone glycosides from Coleogyne ramosissima

A benzophenone glucoside and two flavonol glycosides were isolated together with 27 known polyphenols from the aerial parts of Coleogyne ramosissima, and their structures were elucidated by spectroscopic and chemical methods as iriflophenone 2-O-β-glucopyranoside, isorhamnetin 3-O-2(G)-rhamnopyranosylrutinoside-7-O-α-rhamnopyranoside and limocitrin 3-O-rutinoside-7-O-β-glucopyranoside, respectively. (C) 2000 Elsevier Science Ltd.