60439-46-5 Usage
General Description
3-Morpholinopropyl=3,4,5-trimethoxybenzoate is a chemical compound consisting of a morpholine ring attached to a benzene ring with three methoxy groups. The morpholinopropyl group is a three-carbon chain with a morpholine ring at the end, while the benzene ring is substituted with three methoxy groups at positions 3, 4, and 5. 3-Morpholinopropyl=3,4,5-trimethoxybenzoate has potential applications in the pharmaceutical industry due to its unique structure, which may allow for interactions with biological targets. It may also have use as a reagent in organic synthesis or as a building block for the development of new compounds with specific properties or functions. Additionally, it could be utilized in research settings to investigate its potential biological activities. Overall, 3-Morpholinopropyl=3,4,5-trimethoxybenzoate is a versatile chemical with potential uses in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 60439-46-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,4,3 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60439-46:
(7*6)+(6*0)+(5*4)+(4*3)+(3*9)+(2*4)+(1*6)=115
115 % 10 = 5
So 60439-46-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H25NO6/c1-20-14-11-13(12-15(21-2)16(14)22-3)17(19)24-8-4-5-18-6-9-23-10-7-18/h11-12H,4-10H2,1-3H3
60439-46-5Relevant articles and documents
Dilazep analogues for the study of equilibrative nucleoside transporters 1 and 2 (ENT1 and ENT2)
Playa, Hilaire,Lewis, Timothy A.,Ting, Amal,Suh, Byung-Chul,Muoz, Benito,Matuza, Robert,Passer, Brent J.,Schreiber, Stuart L.,Buolamwini, John K.
, p. 5801 - 5804 (2015/01/08)
As ENT inhibitors including dilazep have shown efficacy improving oHSV1 targeted oncolytic cancer therapy, a series of dilazep analogues was synthesized and biologically evaluated to examine both ENT1 and ENT2 inhibition. The central diamine core, alkyl chains, ester linkage and substituents on the phenyl ring were all varied. Compounds were screened against ENT1 and ENT2 using a radio-ligand cell-based assay. Dilazep and analogues with minor structural changes are potent and selective ENT1 inhibitors. No selective ENT2 inhibitors were found, although some analogues were more potent against ENT2 than the parent dilazep.
