60454-98-0 Usage
Molar mass
176.21 g/mol the mass of one mole of 1-propoxy-1H-benzotriazole, measured in grams per mole.
Type of compound
Benzotriazole a class of chemical compounds to which 1-propoxy-1H-benzotriazole belongs.
Industrial applications
Corrosion inhibitor used to prevent or slow down the corrosion of metals in industrial and automotive settings.
Specific use
UV-absorber and light stabilizer 1-propoxy-1H-benzotriazole is used to protect plastics, coatings, and polymers from the damaging effects of UV radiation.
Mechanism of action
Absorbing UV radiation the compound protects materials by absorbing harmful UV rays, preventing degradation and discoloration.
Additional uses
Pharmaceutical intermediate, dye and pigment production 1-propoxy-1H-benzotriazole is also employed in the synthesis of pharmaceuticals and the production of dyes and pigments.
Toxicity
Low toxicity the chemical is considered to have a low level of toxicity, making it relatively safe for use.
Environmental impact
Low environmental impact 1-propoxy-1H-benzotriazole is considered to have a minimal effect on the environment, reducing its potential for negative ecological consequences.
Check Digit Verification of cas no
The CAS Registry Mumber 60454-98-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,4,5 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60454-98:
(7*6)+(6*0)+(5*4)+(4*5)+(3*4)+(2*9)+(1*8)=120
120 % 10 = 0
So 60454-98-0 is a valid CAS Registry Number.
60454-98-0Relevant articles and documents
Synthesis and evaluation of 1-hydroxybenzotriazole derivatives: Dual inhibitors of carbonic anhydrase ii and sodium hydrogen exchanger i
Singh, Dhandeep,Singh, Nirmal
, p. 687 - 693 (2021/10/01)
Ischemia reperfusion injury is responsible for impaired graft functioning in organ transplants, cerebral dysfunction, ischemic heart diseases, systemic inflammatory response syndrome, gastrointestinal dysfunction, and multiple organ dysfunction syndromes. Intracellular pH is critical for cell survival in ischemia reperfusion injury. Sodium hydrogen exchanger I and carbonic anhydrase II are critical in the regulation of intracellular pH. Inhibition of sodium hydrogen exchanger I and carbonic anhydrase II during reperfusion is found to ameliorate ischemia reperfusion injury separately. An attempt is made to synthesize dual inhibitors of sodium hydrogen exchanger and carbonic anhydrase to have better potential drug molecule in ischemia reperfusion injury treatment. The hydroxybenzotriazole is considered as a central pharmacophore for this dual activity and 12 derivatives are synthesized. All derivatives are tested for sodium hydrogen exchanger I and carbonic anhydrase II inhibitory activity. The tosylate derivative (12) is found to be the most potent derivative with IC50 158.7± 8.4 μM for carbonic anhydrase II and 31.07 ± 1.06 μM for sodium hydrogen exchanger I. Although the potency is less than standard drugs but this is the first report of dual inhibitor of carbonic anhydrase II and sodium hydrogen exchanger.
