60463-77-6

Basic information

• Product Name: 3-hydroxy-1-methyl-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
• Synonyms: 3-hydroxy-1-methyl-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
• CAS NO: 60463-77-6
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.3059
• Mol File: 60463-77-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 548.3°C at 760 mmHg
• Flash Point: 285.4°C
• Appearance: /
• Density: 1.287g/cm³
• Vapor Pressure: 7.43E-13mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: 3-hydroxy-1-methyl-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-1-methyl-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one(60463-77-6)
• EPA Substance Registry System: 3-hydroxy-1-methyl-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one(60463-77-6)

Safety Data

• Hazardous Substances Data: 60463-77-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H15NO3/c1-18-14-10-6-5-9-13(14)17(21,16(18)20)11-15(19)12-7-3-2-4-8-12/h2-10,21H,11H2,1H3

Upstream product

• 59-48-3 2-oxoindole 
• 61-70-1 N-methyl-2-indolinone 
• 98-86-2 acetophenone 
• 91-56-5 indole-2,3-dione 
• 7257-94-5 1-phenyl-2-(p-tolylsulfonyloxy)ethanone 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 

Downstream Products

• 27230-23-5 (Z)-1-methyl-3-(2-oxo-2-phenylethylidene)dihydroindol-2-one 
• 56680-30-9 1-methyl-1,3-dihydro-3-<2-phenyl-2-oxoethylidene>-2H-indole-2-one 
• 27230-23-5 1-methyl-3-(2-oxo-2-phenylethylidene)indolin-2-one 
• 844-49-5 1-methyl-3-(2-oxo-2-phenylethyl)indolin-2-one 

Relevant articles and documents

Diastereoselective trans Cyclopropanation of 3-Alkylidene Oxindoles with in Situ Generated α-Diazo Carbonyls or α,β-Unsaturated Diazo Compounds

An efficient diastereoselective trans cyclopropanation of 3-alkylidene oxindoles with in situ generated α-diazo carbonyl compounds or α,β-unsaturated diazo compounds under metal-free conditions has been developed to synthesize 3-spirocyclopropyl-2-oxindol

Green catalytic synthesis method of isatin derivative

The invention discloses a green catalytic synthesis method of isatin derivative. The method comprises the following steps: adopting isatin compound and ketone containing alpha-hydrogen as raw materials, adopting water as a solvent to perform Aldol reactio

An unprecedented protocol for the synthesis of 3-hydroxy-3-phenacyloxindole derivatives with indolin-2-ones and α-substituted ketones

An unprecedented reaction between indolin-2-ones and α-substituted ketones has been developed. Using this protocol, a wide range of biologically important 3-hydroxy-3-phenacyloxindole derivatives could be obtained in good yield (up to 93%) under mild reaction conditions. A possible mechanism of this reaction was tentatively proposed based on some control experiments and MS spectrometry analysis.