6047-83-2

Basic information

• Product Name: Sulfonium, [2-(4-bromophenyl)-2-oxoethyl]dimethyl-, bromide
• CAS NO: 6047-83-2
• Molecular Formula: C10H12BrOS.Br
• Molecular Weight: 340.079
• Mol File: 6047-83-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Sulfonium, [2-(4-bromophenyl)-2-oxoethyl]dimethyl-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfonium, [2-(4-bromophenyl)-2-oxoethyl]dimethyl-, bromide(6047-83-2)
• EPA Substance Registry System: Sulfonium, [2-(4-bromophenyl)-2-oxoethyl]dimethyl-, bromide(6047-83-2)

Safety Data

• Hazardous Substances Data: 6047-83-2(Hazardous Substances Data)

Upstream product

• 75-18-3 dimethylsulfide 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 2126-07-0 (4-bromophenyl)(3-phenyl-4,5-dihydroisoxazol-5-yl)methanone 
• 29555-25-7 benzo[b]furan-2-yl-(4-bromophenyl)-methanone 

Relevant articles and documents

Water-Mediated Intramolecular Cyclization/Oxidation of α-Carbonyl Sulfur Ylides: Synthesis of Corey-Chaykovsky Reagent Type Heterocycles

A new class of Corey-Chaykovsky reagent type five-membered heterocycles with an oxosulfonium ylide moiety has been synthesized by the water-mediated intramolecular cyclization/oxidation of α-carbonyl sulfur ylides generated in situ from sulfonium salts under mild conditions.

Catalyst-Free Synthesis of 2,3-Dihydrobenzofurans via a Formal [4+1] Annulation of Propargylamines with Sulfur Ylides

A simple, general route to the 2,3-dihydrobenzofurans substituted at C3 by an aryethynyl or aryl group, starting from propargylamine and its derivatives with benzoyl sulfonium salts, has been developed. This reaction involved an in situ generated o-quinone methide (o-QM) intermediate followed by [4+1] annulation with sulfur ylides. Notably, this protocol's features include moderate to excellent yields and remarkable diastereoselectivity (>20:1 dr in general), easy performance, as well as applicability to versatile 2,3-dihydrobenzofurans with aryethynyl or an aryl group via C-C and C-O bond formation in one pot without any catalyst in an aqueous mixed solvent.

1,6-Conjugated Addition-Mediated [2+1] Annulation: Approach to Spiro[2.5]octa-4,7-dien-6-one

A formal 1,6-conjugated addition-mediated [2+1] annulation to synthesize spiro[2.5]octa-4,7-dien-6-one with p-quinone methides and sulfur ylides has been described. This domino-type process was highly diastereoselective and exhibited good functional group tolerance and scalability without the use of metals and bases.