60544-07-2Relevant articles and documents
The silver catalyzed direct C-H functionalization of quinones with dialkyl amides
Pandaram, Sakthivel,Adarsh Krishna,Ilangovan, Andivelu
, p. 3027 - 3031 (2020)
DMA and other dialkylamides were successfully used as synthons for the C-H functionalization of quinones. This novel amidoalkylation reaction works with a variety of substituted quinones and dialkyl/alkyl amides, such as DMF, NMP and NMA, and the corresponding products were obtained in moderate to good yields. The amidoalkylation of quinones is demonstrated for the first time. A suitable mechanism and the synthetic utility of these compounds are demonstrated. The molecular docking of compound 5 with an Alzheimer's disease (AD) associated AChE target site was studied.
Approach to the Synthesis of Unsymmetrical/Symmetrical Maleimides via Desulfitative Arylation at Different Temperatures
Abbasnia, Masoumeh,Sheykhan, Mehdi,Ghaffari, Tahereh,Safari, Elham
, p. 11688 - 11698 (2020/10/23)
New routes toward selective synthesis of both mono-and diaryl maleimides have been innovated. The mere requirement to this end is through the increase of temperature. The method works effectively for maleic anhydride and maleic acid as well. Also, the fir
CuI/Cu(OTf)2/DMSO system-catalyzed intramolecular oxidative cyclization of (o-alkynyl)arylketones: Efficient synthesis of 1,4-naphthoquinones
Zhou, Bingwei,Liu, Qian,Wang, Heng,Jin, Hongwei,Liu, Yunkui
, p. 3815 - 3821 (2019/06/14)
A concise and efficient method for the synthesis of 1,4-naphthoquinones has been successfully developed involving a CuI/Cu(OTf)2/DMSO system-catalyzed intramolecular oxidative cyclization of (o-alkynyl)arylketones. The present protocol provided a novel approach to access functionalized 1,4-naphthoquinones from non-naphthoquinone precursors with good selectivity and functional group tolerance.