60562-15-4 Usage
Description
1,2-DILAUROYL-SN-GLYCEROL, also known as 12:0 DG, is a type of sn-1,2-diacylglycerol that features short saturated acyl side chains (C4-C10). It is a significant component in lipidomics studies and has various applications across different industries due to its unique properties.
Uses
Used in Pharmaceutical and Biomedical Research:
1,2-DILAUROYL-SN-GLYCEROL is used as an internal standard for spiking serum samples for liquid chromatography-mass spectrometry analysis. It ensures accurate and reliable quantification of lipids in biological samples, which is crucial for understanding various diseases and their underlying mechanisms.
Used in Cell Biology Studies:
In cell biology, 1,2-DILAUROYL-SN-GLYCEROL is used as an internal standard for spiking RAW 264.7 cells, a widely used macrophage cell line, for mass spectroscopy studies. This application aids in the investigation of cellular processes and the role of lipids in immune responses.
Used in Lipidomics Research:
1,2-DILAUROYL-SN-GLYCEROL is employed in reverse phase liquid chromatography coupled with a mass spectrometer for lipidomics studies of human plasma and serum samples. It serves as a valuable tool for the comprehensive analysis of lipid profiles, which can provide insights into various metabolic and inflammatory conditions.
Overall, 1,2-DILAUROYL-SN-GLYCEROL plays a vital role in various research and diagnostic applications, particularly in the fields of pharmaceuticals, biomedical research, cell biology, and lipidomics. Its use as an internal standard contributes to the accuracy and reliability of experimental results, ultimately enhancing our understanding of biological processes and disease mechanisms.
Biochem/physiol Actions
1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.
Check Digit Verification of cas no
The CAS Registry Mumber 60562-15-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,6 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60562-15:
(7*6)+(6*0)+(5*5)+(4*6)+(3*2)+(2*1)+(1*5)=104
104 % 10 = 4
So 60562-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3/t25-/m0/s1
