605659-03-8

Basic information

• Product Name: 4,4-DIFLUOROAMINOETHYLPIPERIDINE
• Synonyms: 2-(4,4-DIFLUOROPIPERIDIN-1-YL)ETHYLAMINE;4,4-DIFLUOROAMINOETHYLPIPERIDINE;1-Piperidineethanamine,4,4-difluoro-;1-Piperidineethanamine,4,4-difluoro-(9CI);4,4-DIFLUORO-1-PIPERIDINEETHANAMINE;2-(4,4-Difluoropiperidin-1-yl)ethanamine
• CAS NO: 605659-03-8
• Molecular Formula: C₇H₁₄F₂N₂
• Molecular Weight: 164.1962664
• Product Categories: PIPERIDINE;AMINETERTIARY;HALIDE
• Mol File: 605659-03-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 196.5 °C at 760 mmHg
• Flash Point: 72.6 °C
• Appearance: /
• Density: 1.11 g/cm³
• Vapor Pressure: 0.398mmHg at 25°C
• Refractive Index: 1.458
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4,4-DIFLUOROAMINOETHYLPIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-DIFLUOROAMINOETHYLPIPERIDINE(605659-03-8)
• EPA Substance Registry System: 4,4-DIFLUOROAMINOETHYLPIPERIDINE(605659-03-8)

Safety Data

• Hazardous Substances Data: 605659-03-8(Hazardous Substances Data)

Usage

General Description

4,4-Difluoroaminoethylpiperidine is a chemical compound with the molecular formula C8H15F2N. It is an organofluorine compound that contains a piperidine ring structure with two fluorine atoms and an aminoethyl group attached to the nitrogen atom. 4,4-DIFLUOROAMINOETHYLPIPERIDINE is used in organic synthesis as a building block for the production of various pharmaceuticals, agrochemicals, and advanced materials. It is also used as a reagent in the preparation of various functionalized compounds. The presence of fluorine in the molecule imparts unique properties to the compound, making it valuable for the development of diverse chemical products. Additionally, 4,4-difluoroaminoethylpiperidine may also have potential applications in the field of medicinal chemistry and drug discovery due to its structural features.

InChI:InChI=1/C7H14F2N2/c8-7(9)1-4-11(5-2-7)6-3-10/h1-6,10H2

Upstream product

• 824413-96-9 2-(4,4-difluoropiperidin-1-yl)acetonitrile 
• 21987-29-1 4,4-difluoropiperidine 

Downstream Products

• 1262836-23-6 C₂₅H₂₃F₅N₄O₂ 
• 1117686-32-4 N-[2-(4,4-difluoropiperidin-1-yl)ethyl]-4-{[4-(2,6-dimethyl-pyridin-3-yl)oxypyridin-2-yl]amino}benzamide 

Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS

Compounds of formula (Ι') that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Aryl compounds with aminoalkyl substituents and their use

The present application relates to novel aryl compounds with aminoalkyl substituents, to processes for their preparation, to their use for treatment and/or prevention of diseases and to their use for the preparation of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be carried out as monotherapy or also in combination with other medicaments or further therapeutic measures.