606-06-4

Basic information

• Product Name: COENZYME Q2
• Synonyms: COENZYME Q2;2,3-DIMETHOXY-5-METHYL-GERANYL-1,4-BENZOQUINONE;2,3-dimethoxy-5-methyl-6-[poly0-2-methylbutenyl(2)]-1,4-quinone;2,3-dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone;2-[(2E)-3,7-dimethylocta-2,6-dienyl]-5,6-dimethoxy-3-methyl-cyclohexa-2,5-diene-1,4-dione;Ubiquinone Q2;2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone, Ubiquinone-10;2,3-Dimethoxy-5-methyl-6-[(2E)-3,7-dimethyl-2,6-octadienyl]-1,4-benzoquinone
• CAS NO: 606-06-4
• Molecular Formula: C₁₉H₂₆O₄
• Molecular Weight: 318.41
• EINECS: 206-147-9
• Mol File: 606-06-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 465.8±45.0 °C(Predicted)
• Appearance: solid
• Density: 1.05±0.1 g/cm3(Predicted)
• Storage Temp.: −20°C
• Stability: Stable, but light and heat sensitive. Store in the dark at -20 C. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: COENZYME Q2(CAS DataBase Reference)
• NIST Chemistry Reference: COENZYME Q2(606-06-4)
• EPA Substance Registry System: COENZYME Q2(606-06-4)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 606-06-4(Hazardous Substances Data)

Usage

Description

Coenzyme Q2, also known as ubiquinone, is a lipid-soluble benzoquinone compound that functions as a redox carrier in the mitochondrial respiratory chain of eukaryotic cells. It plays a crucial role in the electron transport chain, facilitating the production of ATP, the primary energy source for cellular processes. Coenzyme Q2 is also known for its antioxidant properties, protecting cells from oxidative damage and maintaining overall cellular health.

Uses

Used in Pharmaceutical Industry:
Coenzyme Q2 is used as a therapeutic agent for various health conditions, including heart disease, muscular dystrophy, and neurodegenerative disorders. Its role in energy production and antioxidant defense makes it a valuable compound for supporting cellular function and overall health.
Used in Cosmetic Industry:
Coenzyme Q2 is used as an ingredient in skincare products for its antioxidant properties. It helps to protect the skin from environmental stressors and supports the skin's natural defense mechanisms, promoting a healthy and youthful appearance.
Used in Research Applications:
Coenzyme Q2 is used as a research tool to investigate the interaction of coenzyme Q with phosphatidylethanolamine membranes. This helps scientists to better understand the role of coenzyme Q in cellular processes and its potential applications in various fields.

Biochem/physiol Actions

Acts as an electron carrier and antioxidant in humans

InChI:InChI=1/C19H26O4/c1-12(2)8-7-9-13(3)10-11-15-14(4)16(20)18(22-5)19(23-6)17(15)21/h8,10H,7,9,11H2,1-6H3/b13-10+

Upstream product

• 152984-32-2 4,5-dimethoxy-2-methyltricyclo[6.2.1.0^2,7]undeca-4,9-diene-3,6-dione 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 106-44-5 p-cresol 
• 35896-58-3 2,3,4,5-tetramethoxytoluene 
• 5677-55-4 ubiquinone Q₂ 
• 1128-32-1 2,3-dimethoxy-5-methylphenol 
• 609-25-6 5-methylpyrogallol 
• 605-94-7 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 
• 6138-90-5 trans-geranyl bromide 
• 84551-67-7 1-methyl ether of 2,3-dimethoxy-5-methyl-6-geranylhydroquinone 
• 203059-93-2 4a-((E)-3,7-Dimethyl-octa-2,6-dienyl)-6,7-dimethoxy-8a-methyl-1,4,4a,8a-tetrahydro-1,4-methano-naphthalene-5,8-dione 
• 106-24-1 Geraniol 
• 3066-90-8 2,3-dimethoxy-5-methylbenzene-1,4-diol 
• 106-25-2 Nerol 

Downstream Products

• 96358-48-4 2,3-dimethoxy-5-methyl-6-(3-methyl-6-chloro-7-methylene-2E-octenyl)-1,4-benzoquinone 
• 5677-55-4 ubiquinone Q₂ 
• 83036-57-1 (E)-1-(3,7-dimethylocta-2,6-dien-1-yl)-2,3,4,5-tetramethoxy-6-methylbenzene 
• 85228-79-1 1-<(2E)-6,7-epoxy-3,7-dimethyloct-2-enyl>-2,3,4,5-tetramethoxy-6-methylbenzene 
• 849034-07-7 3-bromo-2,6-dimethyl-8-(2-methyl-3,4,5,6-tetramethoxyphenyl)oct-6-en-2-ol 
• 77878-71-8 6-(7-formyl-3-methyl-2,6-octadienyl)-2,3-dimethoxy-5-methylhydroquinone diacetate 
• 122907-52-2 6-(8-hydroxy-3,7-dimethyl-2,6-octadienyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone 

Relevant articles and documents

New efficient synthesis of ubiquinones

A strategy for the ecofriendly and high-yielding synthesis of ubiquinones starting from simple materials and using mild conditions is reported. CoQ1, CoQ2, CoQ3, and CoQ9 were prepared. Copyright Taylor & Francis Group, LLC.

A practical procedure for the synthesis of 3-((E)-5-(2,3,4,5-tetramethoxy- 6-methylphenyl)-3-methylpent-3-enyl)-2,2-dimethyloxirane

-

Rapid photochemical generation of ubiquinol through a radical pathway: An avenue for probing submillisecond enzyme kinetics

-