60624-39-7

Basic information

• Product Name: 2-AMINO-N-(4-ETHYL-PHENYL)-BENZAMIDE
• Synonyms: 2-AMINO-N-(4-ETHYL-PHENYL)-BENZAMIDE;2-amino-N-(4-ethylphenyl)benzamide hydrochloride;AG-205/05987056;BAS 00159603;Enamine_005778;IDI1_008013;Oprea1_018398;Oprea1_384355
• CAS NO: 60624-39-7
• Molecular Formula: C₁₅H₁₆N₂O
• Molecular Weight: 240.3
• Mol File: 60624-39-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 338.8°Cat760mmHg
• Flash Point: 158.7°C
• Appearance: /
• Density: 1.181g/cm³
• Vapor Pressure: 9.6E-05mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 2-AMINO-N-(4-ETHYL-PHENYL)-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-(4-ETHYL-PHENYL)-BENZAMIDE(60624-39-7)
• EPA Substance Registry System: 2-AMINO-N-(4-ETHYL-PHENYL)-BENZAMIDE(60624-39-7)

Safety Data

• Hazardous Substances Data: 60624-39-7(Hazardous Substances Data)

Usage

Classification

Organic compound, benzamide

Functional groups

Primary amine group, amide functional group

Substituents

Ethyl-substituted phenyl group

Potential applications

Chemical research, pharmaceutical and medicinal chemistry

Specific uses and effects

Not widely studied and reported

InChI:InChI=1/C15H16N2O/c1-2-11-7-9-12(10-8-11)17-15(18)13-5-3-4-6-14(13)16/h3-10H,2,16H2,1H3,(H,17,18)

Upstream product

• 118-48-9 isatoic anhydride 
• 589-16-2 4-aminoethylbenzene 

Downstream Products

• 60624-47-7 2-(2,2-Dicyano-vinylamino)-N-(4-ethyl-phenyl)-benzamide 
• 19826-42-7 3-(4-ethylphenyl)-2-methylquinazolin-4(3H)-one 
• 22874-41-5 3-(4-ethylphenyl)quinazolin-4(3H)-one 
• 133040-88-7 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-ethyl-phenyl)-3H-quinazolin-4-one 
• 60624-42-2 (E)-2-Cyano-3-[2-(4-ethyl-phenylcarbamoyl)-phenylamino]-acrylic acid ethyl ester 

Relevant articles and documents

Ionic liquid supported on magnetic nanoparticles as a novel reusable nanocatalyst for the efficient synthesis of tetracyclic quinazoline compounds

A magnetic ionic liquid supported on γ-Fe2O3 nanocatalyst was synthesized successfully and characterized by Fourier transform infrared spectroscopy, vibrating sample magnetometry, thermogravimetric analysis, differential scanning calorimetry, X-ray diffraction and scanning electron microscopy. The resulting nano-Fe3O4-supported, ionic liquid was an efficient catalyst for preparation of a series of tetracyclic quinazoline compounds by three components reaction of a mixture of isatoic anhydride and amine with ninhydrin in PEG and the desired products were obtained in good to excellent yields. High efficiency, waste-free, mild reaction conditions, effortless magnetic recovery and reusability up to four continuous cycles are the noteworthy features of the currently employed heterogeneous catalytic system.

Montmorillonite K-10 catalysed solvent-free synthesis of 2,3-disubstituted-4(3H)quinazolinones under microwave irradiation

An efficient and rapid synthesis of 2,3-disubstituted-4(3H)quinazolinones by condensation of 2-aminobenzamide (substituted anthraniamides) with orthoesters in the presence of K-10 clay under solvent free conditions using microwave irradiation or classical heating is described.