60680-97-9 Usage
Derivative of indole
This compound is derived from the indole structure, which is a bicyclic aromatic organic compound important in organic synthesis and pharmaceutical research.
Nitrile group
The presence of a nitrile group (C≡N) in the compound contributes to its reactivity and potential applications in various chemical reactions.
Methyl group attachment
A methyl group (CH3) is attached to the carbon atom at position 1, which influences the compound's properties and reactivity.
Importance in organic synthesis
1H-Indole-2-carbonitrile, 1-methylserves as a precursor for the synthesis of various biologically active compounds and pharmaceuticals, making it a valuable building block in organic chemistry.
Building block for dyes, pigments, and agricultural chemicals
The compound is also used as a starting material in the production of dyes, pigments, and agricultural chemicals, highlighting its versatility in different industries.
Potential pharmacological properties
1H-Indole-2-carbonitrile, 1-methylhas been investigated for its potential pharmacological properties, including its role as an anti-inflammatory and anticancer agent, indicating its potential for therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 60680-97-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,6,8 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60680-97:
(7*6)+(6*0)+(5*6)+(4*8)+(3*0)+(2*9)+(1*7)=129
129 % 10 = 9
So 60680-97-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2/c1-12-9(7-11)6-8-4-2-3-5-10(8)12/h2-6H,1H3
60680-97-9Relevant articles and documents
Boron(III)-Catalyzed C2-Selective C?H Borylation of Heteroarenes
Zhong, Qi,Qin, Shengxiang,Yin, Youzhi,Hu, Jiajun,Zhang, Hua
, p. 14891 - 14895 (2018/10/20)
A BF3?Et2O-catalyzed C2-selective C?H borylation of indoles with bis(pinacolato)diboron was developed to afford indole-2-boronic acid pinacol esters. A variety of functional groups were tolerated, and other heteroarenes like pyrrole and benzo[b]thiophene were also suitable substrates. An electrophilic substitution mechanism was proposed based on the preliminary mechanistic studies. This novel transformation utilizes simple and cheap BF3?Et2O as catalyst and exhibits unusual C2 regioselectivity, providing a significant non-transition-metal-catalyzed C?H borylation and an efficient method towards the synthesis of C2-functionalized heteroarenes.
