606932-82-5Relevant articles and documents
Synthesis and structure-activity relationship studies of cinnamic acid-based novel thiazolidinedione antihyperglycemic agents
Neogi, Partha,Lakner, Fredrick J.,Medicherla, Satyanarayana,Cheng, Jin,Dey, Debendranath,Gowri, Maya,Nag, Bishwajit,Sharma, Somesh D.,Pickford, Lesley B.,Gross, Coleman
, p. 4059 - 4067 (2007/10/03)
A number of 2,4-thiazolidinedione derivatives of -phenyl substituted cinnamic acid were synthesized and studied for their PPAR agonist activity. The E-isomer of cinnamic acid, 11, showed moderate PPAR transactivation. The corresponding Z-isomer, 23, and d