60722-66-9 Usage
Class
Pyrimidines
Common uses
Intermediate in the synthesis of pharmaceuticals and agrochemicals
Biological activities
Inhibition of the enzyme dihydrofolate reductase, potential antifungal and antibacterial properties
Physical properties
White to off-white crystalline powder, molecular weight of 220.2 g/mol, melting point of 180-183 degrees Celsius
Importance
Significant compound in the field of medicinal chemistry due to its diverse biological activities and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 60722-66-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,7,2 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 60722-66:
(7*6)+(6*0)+(5*7)+(4*2)+(3*2)+(2*6)+(1*6)=109
109 % 10 = 9
So 60722-66-9 is a valid CAS Registry Number.
60722-66-9Relevant articles and documents
SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS
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Page/Page column 172; 173; 174, (2013/05/09)
Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.
